pEGFP-C1-ER alpha | Addgene 28230 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

pEGFP-C1-ER alpha

catalog :

28230

citations: 15

Reference
Kelava I, Chiaradia I, Pellegrini L, Kalinka A, Lancaster M. Androgens increase excitatory neurogenic potential in human brain organoids. Nature. 2022;602:112-116 pubmed publisher
Nguyen Hoang A, Hoe K, Lee S. CSNK1G2 differently sensitizes tamoxifen-induced decrease in PI3K/AKT/mTOR/S6K and ERK signaling according to the estrogen receptor existence in breast cancer cells. PLoS ONE. 2021;16:e0246264 pubmed publisher
Sanawar R, Mohan Dan V, Santhoshkumar T, Kumar R, Pillai M. Estrogen receptor-α regulation of microRNA-590 targets FAM171A1-a modifier of breast cancer invasiveness. Oncogenesis. 2019;8:5 pubmed publisher
Hassan A, Bagu E, Lévesque M, Patten S, Benhadjeba S, Edjekouane L, et al. The 17β-estradiol induced upregulation of the adhesion G-protein coupled receptor (ADGRG7) is modulated by ESRα and SP1 complex. Biol Open. 2019;8: pubmed publisher
Lillo Osuna M, García López J, El Ayachi I, Fatima I, Khalid A, Kumpati J, et al. Activation of Estrogen Receptor Alpha by Decitabine Inhibits Osteosarcoma Growth and Metastasis. Cancer Res. 2019;79:1054-1068 pubmed publisher
Kuo P, Tseng J, Chen H, Wu C, Omar H, Wang C, et al. Identification of SEPTIN12 as a novel target of the androgen and estrogen receptors in human testicular cells. Biochimie. 2019;158:1-9 pubmed publisher
Watanabe K, Yamamoto S, Sakaguti S, Isayama K, Oka M, Nagano H, et al. A novel somatic mutation of SIN3A detected in breast cancer by whole-exome sequencing enhances cell proliferation through ERα expression. Sci Rep. 2018;8:16000 pubmed publisher
Pedersen K, Chodavarapu H, Lazartigues E. Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2. J Endocr Soc. 2017;1:370-384 pubmed publisher
Ferraiuolo R, Tubman J, Sinha I, Hamm C, Porter L. The cyclin-like protein, SPY1, regulates the ER? and ERK1/2 pathways promoting tamoxifen resistance. Oncotarget. 2017;8:23337-23352 pubmed publisher
Huang J, Woods P, Normolle D, Goff J, Benos P, Stehle C, et al. Downregulation of estrogen receptor and modulation of growth of breast cancer cell lines mediated by paracrine stromal cell signals. Breast Cancer Res Treat. 2017;161:229-243 pubmed publisher
Besse Patin A, LÃ©veillÃ© M, Oropeza D, Nguyen B, Prat A, Estall J. Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-Î³ Coactivator 1Î± to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease. Gastroenterology. 2017;152:243-256 pubmed publisher
Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher
Kucinska M, Girón M, Piotrowska H, Lisiak N, Granig W, Lopez Jaramillo F, et al. Novel Promising Estrogenic Receptor Modulators: Cytotoxic and Estrogenic Activity of Benzanilides and Dithiobenzanilides. PLoS ONE. 2016;11:e0145615 pubmed publisher
Toy W, Shen Y, Won H, Green B, Sakr R, Will M, et al. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat Genet. 2013;45:1439-45 pubmed publisher
Stenoien D, Mancini M, Patel K, Allegretto E, Smith C, Mancini M. Subnuclear trafficking of estrogen receptor-alpha and steroid receptor coactivator-1. Mol Endocrinol. 2000;14:518-34 pubmed

product information

Catalog Number :

28230

Product Name :

pEGFP-C1-ER alpha

article :

doi	10.1210/mend.14.4.0436
id	4074
pubmed_id	10770489

bacterial resistance :

Kanamycin

cloning :

backbone

pEGFP-C1

backbone_mutation

backbone_origin

Clontech

backbone_size

4731

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

Tzukerman MT, Esty A, Santiso-Mere D, Danielian P, Parker MG, Stein RB, Pike JW, McDonnell DP 1994 Human estrogen receptor transactivational capacity is determined by both cellular and promoter context and mediated by two functionally distinct intramolecular regions. Mol Endocrinol 8:21 30

growth strain :

Mammalian expression of Estrogen Receptor alpha fused to EGFP

growth temp :

DH5 alpha, XL10G

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	BamHI
cloning_site_5	Kpn I
promoter
sequencing_primer_3	EGFP-N
sequencing_primer_5	EGFP-C
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	ER, ESR, ESRA, ESTRR, Era, NR3A1
gene	ESR1
id	2099

genbank_ids

NM_000125

mutation

name

Estrogen Receptor alpha

shRNA_sequence

size

1789

species

9606

Homo sapiens