This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
wtTDP43tdTOMATOHA
catalog :
28205
citations: 13
Reference
Liang Y, Willey S, Chung Y, Lo Y, Miao S, Rundell S, et al. Intracellular RNA and DNA tracking by uridine-rich internal loop tagging with fluorogenic bPNA. Nat Commun. 2023;14:2987 pubmed publisher
Jung K, Sun J, Hsiung C, Lian X, Liu Y, Zhang X. Nuclear bodies protect phase separated proteins from degradation in stressed proteome. bioRxiv. 2023;: pubmed publisher
Cascella R, Bigi A, Riffert D, Gagliani M, Ermini E, Moretti M, et al. A quantitative biology approach correlates neuronal toxicity with the largest inclusions of TDP-43. Sci Adv. 2022;8:eabm6376 pubmed publisher
Woo T, Yoon M, Kang S, Park S, Cho J, Hwang Y, et al. Novel chemical inhibitor against SOD1 misfolding and aggregation protects neuron-loss and ameliorates disease symptoms in ALS mouse model. Commun Biol. 2021;4:1397 pubmed publisher
Baek M, Choe Y, Bannwarth S, Kim J, Maitra S, Dorn G, et al. TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro. Nat Commun. 2021;12:1924 pubmed publisher
Carter G, Hsiung C, Simpson L, Yang H, Zhang X. N-terminal Domain of TDP43 Enhances Liquid-Liquid Phase Separation of Globular Proteins. J Mol Biol. 2021;433:166948 pubmed publisher
Ito S, Shiraishi M, Tsuchihashi K, Takatsuka R, Yamamoto J, Kuraoka I, et al. Fluorescence detection of DNA mismatch repair in human cells. Sci Rep. 2018;8:12181 pubmed publisher
Pinarbasi E, Cagatay T, Fung H, Li Y, Chook Y, Thomas P. Active nuclear import and passive nuclear export are the primary determinants of TDP-43 localization. Sci Rep. 2018;8:7083 pubmed publisher
Gregory J, Whiten D, Brown R, Barros T, Kumita J, Yerbury J, et al. Clusterin protects neurons against intracellular proteotoxicity. Acta Neuropathol Commun. 2017;5:81 pubmed publisher
Woo J, Liu T, Trotter C, Fang C, De Narvaez E, LePochat P, et al. Loss of function CHCHD10 mutations in cytoplasmic TDP-43 accumulation and synaptic integrity. Nat Commun. 2017;8:15558 pubmed publisher
Liu Y, Miao K, Dunham N, Liu H, Fares M, Boal A, et al. The Cation-π Interaction Enables a Halo-Tag Fluorogenic Probe for Fast No-Wash Live Cell Imaging and Gel-Free Protein Quantification. Biochemistry. 2017;56:1585-1595 pubmed publisher
Farrawell N, Lambert Smith I, Warraich S, Blair I, Saunders D, Hatters D, et al. Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions. Sci Rep. 2015;5:13416 pubmed publisher
Yang C, Tan W, Whittle C, Qiu L, Cao L, Akbarian S, et al. The C-terminal TDP-43 fragments have a high aggregation propensity and harm neurons by a dominant-negative mechanism. PLoS ONE. 2010;5:e15878 pubmed publisher
product information
Catalog Number :
28205
Product Name :
wtTDP43tdTOMATOHA
article :
doi10.1371/journal.pone.0015878
id4068
pubmed_id21209826
bacterial resistance :
Ampicillin
cloning :
backbonepCAG-EGFP/RFP-int
backbone_mutation
backbone_origin
backbone_size5310
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
DH5a in LB media at 37C
origin :
37
pi :
alt_names
TDP43
cloning
clone_methodRestriction Enzyme
cloning_site_3Mlu1
cloning_site_5EcoRV
promoter
sequencing_primer_3
sequencing_primer_5TTCCTACAGCTCCTGGGCAA
site_3_destroyed
site_5_destroyed1
entrez_gene
aliasesALS10, TDP-43
geneTARDBP
id23435
genbank_ids
NM_007375
mutation
nameTar DNA binding protein
shRNA_sequence
size2800
species
9606
Homo sapiens
tags
locationC terminal on insert
tagtdtomato
locationC terminal on insert
tagHA tag
resistance markers :
594
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA