This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
145-pGL3ctrl-3' UTR
catalog :
28175
citations: 5
Reference
Cen B, Lang J, Du Y, Wei J, Xiong Y, Bradley N, et al. Prostaglandin E2 Induces MIR675-5p to Promote Colorectal Tumor Metastasis via Modulation of p53 Expression. Gastroenterology. 2019;: pubmed publisher
Raut S, Singh G, Rastogi B, Saikia U, Mittal A, Dogra N, et al. miR-30c and miR-181a synergistically modulate p53-p21 pathway in diabetes induced cardiac hypertrophy. Mol Cell Biochem. 2016;417:191-203 pubmed publisher
Towers C, Guarnieri A, Micalizzi D, Harrell J, Gillen A, Kim J, et al. The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p. Nat Commun. 2015;6:10077 pubmed publisher
Choi Y, Lee H, Lee Y, Shim D, Seo S. RRP12 is a crucial nucleolar protein that regulates p53 activity in osteosarcoma cells. Tumour Biol. 2016;37:4351-8 pubmed publisher
Chen J, Kastan M. 5'-3'-UTR interactions regulate p53 mRNA translation and provide a target for modulating p53 induction after DNA damage. Genes Dev. 2010;24:2146-56 pubmed publisher
product information
Catalog Number :
28175
Product Name :
145-pGL3ctrl-3' UTR
article :
doi10.1101/gad.1968910
id4059
pubmed_id20837656
bacterial resistance :
Ampicillin
cloning :
backbonepGL3-control vector
backbone_mutation
backbone_originPromega
backbone_size5256
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI (3'UTR)
cloning_site_5HindIII/NcoI (5'UTR)
promoter
sequencing_primer_3pGL3 spb2
sequencing_primer_5pGL3ctrl luc spb1
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutationNote that insert length is based on sum of the 2 UTRs (145+1207)
nameLuciferase flanked by tp53 UTRs
shRNA_sequence
size1352
species
9606
Homo sapiens
tags
resistance markers :
915
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA