This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pGEX-EZH2
catalog :
28060
citations: 7
Reference
Guo C, Liu Z, Zhang H. DNA 6mA demethylase ALKBH1 regulates DDX18 expression to promote proliferation of human head and neck squamous cell carcinoma. Cell Oncol (Dordr). 2023;46:1097-1111 pubmed publisher
Chen J, Zhao H, Lazarenko O, Blackburn M, Shankar K. Maternal regulation of SATB2 in osteo-progeniters impairs skeletal development in offspring. FASEB J. 2020;34:2511-2523 pubmed publisher
Caruso L, Martin K, Lauretti E, Hulse M, Siciliano M, Lupey Green L, et al. Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage. Oncotarget. 2018;9:10585-10605 pubmed publisher
Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Mol Cell. 2018;69:279-291.e5 pubmed publisher
Rajabi H, Hiraki M, Tagde A, Alam M, Bouillez A, Christensen C, et al. MUC1-C activates EZH2 expression and function in human cancer cells. Sci Rep. 2017;7:7481 pubmed publisher
Wen S, Tian J, Niu Y, Li L, Yeh S, Chang C. ASC-J9(®), and not Casodex or Enzalutamide, suppresses prostate cancer stem/progenitor cell invasion via altering the EZH2-STAT3 signals. Cancer Lett. 2016;376:377-86 pubmed publisher
Wei Y, Chen Y, Li L, Lang J, Yeh S, Shi B, et al. CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells. Nat Cell Biol. 2011;13:87-94 pubmed publisher
product information
Catalog Number :
28060
Product Name :
pGEX-EZH2
article :
doi10.1038/ncb2139
id4032
pubmed_id21131960
bacterial resistance :
Ampicillin
cloning :
backbonepGEX
backbone_mutation
backbone_originAmersham
backbone_size4900
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5pGEX 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesENX-1, ENX1, EZH2b, KMT6, KMT6A, WVS, WVS2
geneEZH2
id2146
genbank_ids
mutation
nameEZH2
shRNA_sequence
size2400
species
9606
Homo sapiens
tags
locationN terminal on insert
tagGST
resistance markers :
215
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA