Flag-cIAP2/pRK5 | Addgene 27973 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Addgene

product type :

cDNA

product name :

Flag-cIAP2/pRK5

catalog :

27973

citations: 7

Reference
Lasso G, Mayer S, Winkelmann E, Chu T, Elliot O, Patiño Galindo J, et al. A Structure-Informed Atlas of Human-Virus Interactions. Cell. 2019;178:1526-1541.e16 pubmed publisher
Wang S, Liu Z, Wang J, Wang Y, Liu J, Ji X, et al. The triptolide-induced apoptosis of osteoclast precursor by degradation of cIAP2 and treatment of rheumatoid arthritis of TNF-transgenic mice. Phytother Res. 2019;33:342-349 pubmed publisher
Högstrand K, Darmanin S, Forshell T, Grandien A. Transformation of mouse T cells requires MYC and AKT activity in conjunction with inhibition of intrinsic apoptosis. Oncotarget. 2018;9:21396-21410 pubmed publisher
Mohr A, Deedigan L, Jencz S, Mehrabadi Y, Houlden L, Albarenque S, et al. Caspase-10: a molecular switch from cell-autonomous apoptosis to communal cell death in response to chemotherapeutic drug treatment. Cell Death Differ. 2018;25:340-352 pubmed publisher
Yu X, Deng Q, Li W, Xiao L, Luo X, Liu X, et al. Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFÎ± and ROS production. Oncotarget. 2015;6:1995-2008 pubmed
Zhou A, Shen R, Kim E, Lock Y, Xu M, Chen Z, et al. IKK?-mediated tumorigenesis requires K63-linked polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 ubiquitin ligase complex. Cell Rep. 2013;3:724-33 pubmed publisher
Hu S, Du M, Park S, Alcivar A, Qu L, Gupta S, et al. cIAP2 is a ubiquitin protein ligase for BCL10 and is dysregulated in mucosa-associated lymphoid tissue lymphomas. J Clin Invest. 2006;116:174-81 pubmed

product information

Catalog Number :

27973

Product Name :

Flag-cIAP2/pRK5

article :

doi	10.1172/JCI25641
id	4023
pubmed_id	16395405

bacterial resistance :

Ampicillin

cloning :

backbone

pRK5

backbone_mutation

backbone_origin

backbone_size

promoter

sequencing_primer_3

sequencing_primer_5

vector_types

Mammalian Expression

growth notes :

This plasmid has also been used and described in the following publication: Cellular inhibitor of apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO. Hu et al (J Biol Chem. 2003 Mar 21;278(12):10055-60. Epub 2003 Jan 13. https://www.ncbi.nlm.nih.gov/pubmed/12525502 )

origin :

pi :

alt_names

cloning

clone_method	Restriction Enzyme
cloning_site_3	unknown
cloning_site_5	unknown
promoter	CMV
sequencing_primer_3	SV40pA-R
sequencing_primer_5	CMV-F
site_3_destroyed
site_5_destroyed

entrez_gene

aliases	AIP1, API2, CIAP2, HAIP1, HIAP1, IAP-1, MALT2, MIHC, RNF49, c-IAP2
gene	BIRC3
id	330

genbank_ids

mutation

name

CIAP2

shRNA_sequence

size

species

9606

Homo sapiens