This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pDuet TDP43 WT
catalog :
27462
citations: 6
Reference
François Moutal L, Scott D, Ambrose A, Zerio C, Rodriguez Sánchez M, Dissanayake K, et al. Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology. Sci Rep. 2022;12:8140 pubmed publisher
Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok N, et al. In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2. Leukemia. 2022;36:1313-1323 pubmed publisher
Nguyen T, Kabotyanski E, Reineke L, Shao J, Xiong F, Lee J, et al. The SINEB1 element in the long non-coding RNA Malat1 is necessary for TDP-43 proteostasis. Nucleic Acids Res. 2020;48:2621-2642 pubmed publisher
Wang A, Conicella A, Schmidt H, Martin E, Rhoads S, Reeb A, et al. A single N-terminal phosphomimic disrupts TDP-43 polymerization, phase separation, and RNA splicing. EMBO J. 2018;37: pubmed publisher
Schmidt H, Rohatgi R. In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes. Cell Rep. 2016;16:1228-1236 pubmed publisher
Johnson B, Snead D, Lee J, McCaffery J, Shorter J, Gitler A. TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. J Biol Chem. 2009;284:20329-39 pubmed publisher
product information
Catalog Number :
27462
Product Name :
pDuet TDP43 WT
article :
doi10.1074/jbc.M109.010264
id3958
pubmed_id19465477
bacterial resistance :
Ampicillin
cloning :
backboneGSTDuet (pGV313)
backbone_mutation
backbone_origin
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
Other
Coexpression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5pGEX5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALS10, TDP-43
geneTARDBP
id23435
genbank_ids
mutation
nameTDP-43
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGST
resistance markers :
166
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA