This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRS416Gal TDP43 WT YFP
catalog :
27447
citations: 5
Reference
Bharathi V, Bajpai A, Parappuram I, Patel B. Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis. Biochem Biophys Res Commun. 2022;595:28-34 pubmed publisher
Park S, Park S, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova T, et al. Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLoS Genet. 2019;15:e1008308 pubmed publisher
Prasad A, Raju G, Sivalingam V, Girdhar A, Verma M, Vats A, et al. An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models. Sci Rep. 2016;6:39490 pubmed publisher
Bharathi V, Girdhar A, Prasad A, Verma M, Taneja V, Patel B. Use of ade1 and ade2 mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress in saccharomyces cerevisiae. Yeast. 2016;33:607-620 pubmed publisher
Johnson B, Snead D, Lee J, McCaffery J, Shorter J, Gitler A. TDP-43 is intrinsically aggregation-prone, and amyotrophic lateral sclerosis-linked mutations accelerate aggregation and increase toxicity. J Biol Chem. 2009;284:20329-39 pubmed publisher
product information
Catalog Number :
27447
Product Name :
pRS416Gal TDP43 WT YFP
article :
doi10.1074/jbc.M109.010264
id3958
pubmed_id19465477
bacterial resistance :
Ampicillin
cloning :
backbonepRS416GAL
backbone_mutation
backbone_origin
backbone_size5000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Yeast Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3HindIII
cloning_site_5SpeI
promoter
sequencing_primer_3T3
sequencing_primer_5pRSGal-Fwd GTTAATATACCTCTATACTTTAACGTCAAGGAGA
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesALS10, TDP-43
geneTARDBP
id23435
genbank_ids
mutation
nameTDP-43
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagYFP
resistance markers :
166
tags :
Low Copy
terms :
URA3
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA