This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA3.1-beta-3
catalog :
27289
citations: 12
Reference
Gao Y, Fang Y, Huang Y, Ma R, Chen X, Wang F, et al. MIIP functions as a novel ligand for ITGB3 to inhibit angiogenesis and tumorigenesis of triple-negative breast cancer. Cell Death Dis. 2022;13:810 pubmed publisher
Wang Z, Zhu J. Measurement of Integrin Activation and Conformational Changes on the Cell Surface by Soluble Ligand and Antibody Binding Assays. Methods Mol Biol. 2021;2217:3-15 pubmed publisher
Schmoker A, Perez Pearson L, Cruz C, Colon Flores L, Branfeild S, Pagán Torres F, et al. Defining the TLT-1 interactome from resting and activated human platelets. J Proteomics. 2020;215:103638 pubmed publisher
Soriano A, De Cristofaro T, Di Palma T, Dotolo S, Gokulnath P, Izzo A, et al. PAX8 expression in high-grade serous ovarian cancer positively regulates attachment to ECM via Integrin β3. Cancer Cell Int. 2019;19:303 pubmed publisher
LaFoya B, Munroe J, Pu X, Albig A. Src kinase phosphorylates Notch1 to inhibit MAML binding. Sci Rep. 2018;8:15515 pubmed publisher
Bissey P, Law J, Bruce J, Shi W, Renoult A, Chua M, et al. Dysregulation of the MiR-449b target TGFBI alters the TGF? pathway to induce cisplatin resistance in nasopharyngeal carcinoma. Oncogenesis. 2018;7:40 pubmed publisher
Bhatnagar S, Verma K, Hu Y, Khera E, Priluck A, Smith D, et al. Oral Administration and Detection of a Near-Infrared Molecular Imaging Agent in an Orthotopic Mouse Model for Breast Cancer Screening. Mol Pharm. 2018;15:1746-1754 pubmed publisher
Gasparski A, Ozarkar S, Beningo K. Transient mechanical strain promotes the maturation of invadopodia and enhances cancer cell invasion in vitro. J Cell Sci. 2017;130:1965-1978 pubmed publisher
Wang L, Luo J, Li B, Tian X, Chen L, Huang Y, et al. Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. Nature. 2016;540:579-582 pubmed publisher
Fiore V, Strane P, Bryksin A, White E, Hagood J, Barker T. Conformational coupling of integrin and Thy-1 regulates Fyn priming and fibroblast mechanotransduction. J Cell Biol. 2015;211:173-90 pubmed publisher
Evellin S, Galvagni F, Zippo A, Neri F, Orlandini M, Incarnato D, et al. FOSL1 controls the assembly of endothelial cells into capillary tubes by direct repression of ?v and ?3 integrin transcription. Mol Cell Biol. 2013;33:1198-209 pubmed publisher
Takagi J, Petre B, Walz T, Springer T. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell. 2002;110:599-11 pubmed
product information
Catalog Number :
27289
Product Name :
pcDNA3.1-beta-3
article :
doi10.1016/S0092-8674(02)00935-2
id3918
pubmed_id12230977
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3.1/Myc-His(+)A
backbone_mutation
backbone_originInvitrogen
backbone_size5500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
GPIIIa, CD61
cloning
clone_methodRestriction Enzyme
cloning_site_3unknown
cloning_site_5Hind III
promoter
sequencing_primer_3BGH
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBDPLT16, BDPLT2, BDPLT24, CD61, GP3A, GPIIIa, GT, GT2
geneITGB3
id3690
genbank_ids
NM_000212
mutationn/a
nameintegrin beta 3
shRNA_sequence
size2600
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagMyc
locationC terminal on backbone
tagHis
resistance markers :
496
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA