This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LRP6-m5-pCS2-VSVG
catalog :
27283
citations: 2
Reference
Bozatzi P, Dingwell K, Wu K, Cooper F, Cummins T, Hutchinson L, et al. PAWS1 controls Wnt signalling through association with casein kinase 1α. EMBO Rep. 2018;19: pubmed publisher
Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z, et al. A mechanism for Wnt coreceptor activation. Mol Cell. 2004;13:149-56 pubmed
product information
Catalog Number :
27283
Product Name :
LRP6-m5-pCS2-VSVG
article :
doi10.1016/S1097-2765(03)00484-2
id3914
pubmed_id14731402
bacterial resistance :
Ampicillin
cloning :
backbonepCS2+
backbone_mutation
backbone_origin
backbone_size4095
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
xenopus injection
growth notes :
Dominant inhibitor of Wnt function, similar to LRPT-dC
origin :
37
pi :
alt_names
LRP6
cloning
clone_methodRestriction Enzyme
cloning_site_3Xbal
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADCAD2, STHAG7
geneLRP6
id4040
genbank_ids
mutationChanged S/T of all five PPP(S/T)P motifs to Alanine. 2 of of the 5 sites deviate slightly from the consensus sequence (there is one PPAAP and one CPPAP)
namelow density lipoprotein receptor-related protein 6
shRNA_sequence
size5013
species
9606
Homo sapiens
tags
locationN terminal on insert
tagVSVG
resistance markers :
196
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA