This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LRP6-pCS2-VSVG
catalog :
27282
citations: 4
Reference
Wang X, Zou Y, Chen Z, Li Y, Pan L, Wang Y, et al. Low-density lipoprotein receptor-related protein 6 regulates cardiomyocyte-derived paracrine signaling to ameliorate cardiac fibrosis. Theranostics. 2021;11:1249-1268 pubmed publisher
Colozza G, Jami Alahmadi Y, Dsouza A, Tejeda Muñoz N, Albrecht L, Sosa E, et al. Wnt-inducible Lrp6-APEX2 interacting proteins identify ESCRT machinery and Trk-fused gene as components of the Wnt signaling pathway. Sci Rep. 2020;10:21555 pubmed publisher
Wang Y, Chen Z, Li Y, Ma L, Zou Y, Wang X, et al. Low density lipoprotein receptor related protein 6 (LRP6) protects heart against oxidative stress by the crosstalk of HSF1 and GSK3β. Redox Biol. 2020;37:101699 pubmed publisher
Tamai K, Zeng X, Liu C, Zhang X, Harada Y, Chang Z, et al. A mechanism for Wnt coreceptor activation. Mol Cell. 2004;13:149-56 pubmed
product information
Catalog Number :
27282
Product Name :
LRP6-pCS2-VSVG
article :
doi10.1016/S1097-2765(03)00484-2
id3914
pubmed_id14731402
bacterial resistance :
Ampicillin
cloning :
backbonepCS2+
backbone_mutation
backbone_origin
backbone_size4095
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Other
xenopus injection
growth notes :
Contains full-length human LRP6. Please note that the VSVG-tag was inserted after the LRP6 signal peptide at amino acid 25.
origin :
37
pi :
alt_names
LRP6
cloning
clone_methodRestriction Enzyme
cloning_site_3Xbal
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADCAD2, STHAG7
geneLRP6
id4040
genbank_ids
mutation
namelow density lipoprotein receptor-related protein 6
shRNA_sequence
size5013
species
9606
Homo sapiens
tags
locationN terminal on insert
tagVSVG
resistance markers :
196
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA