This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LRP6-pCS2
catalog :
27242
citations: 6
Reference
Rim E, Nusse R. APEX2-Mediated Proximity Labeling of Wnt Receptor Interactors Upon Pathway Activation. MicroPubl Biol. 2023;2023: pubmed publisher
Taye N, Singh M, Baldock C, Hubmacher D. Secreted ADAMTS-like 2 promotes myoblast differentiation by potentiating WNT signaling. Matrix Biol. 2023;120:24-42 pubmed publisher
Jones M, B xfc chler J, Dufor T, Palomer E, Teo S, Martín Flores N, et al. A genetic variant of the Wnt receptor LRP6 accelerates synapse degeneration during aging and in Alzheimer's disease. Sci Adv. 2023;9:eabo7421 pubmed publisher
Tang L, Spezia M, Chen T, Shin J, Wang F, Stappenbeck F, et al. Oxysterol derivatives Oxy186 and Oxy210 inhibit WNT signaling in non-small cell lung cancer. Cell Biosci. 2022;12:119 pubmed publisher
Sharma K, Choi S, Zhang Y, Nieland T, Long S, Li M, et al. High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development. Cell Rep. 2013;5:1330-41 pubmed publisher
Tamai K, Semenov M, Kato Y, Spokony R, Liu C, Katsuyama Y, et al. LDL-receptor-related proteins in Wnt signal transduction. Nature. 2000;407:530-5 pubmed
product information
Catalog Number :
27242
Product Name :
LRP6-pCS2
article :
doi10.1038/35035117
id3900
pubmed_id11029007
bacterial resistance :
Ampicillin
cloning :
backbonepCS2+
backbone_mutation
backbone_origin
backbone_size4095
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Other
xenopus injection
growth notes :
Use Asp718 to linearize DNA for in vitro transcription by SP6 1st codon starts at 110
origin :
37
pi :
alt_names
LRP6
cloning
clone_methodRestriction Enzyme
cloning_site_3Xbal
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5SP6
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADCAD2, STHAG7
geneLRP6
id4040
genbank_ids
NM_002336
mutation
namelow density lipoprotein receptor-related protein 6
shRNA_sequence
size4980
species
9606
Homo sapiens
tags
resistance markers :
196
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA