This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pBABE-Src-Dasatinib-resistant
catalog :
26980
citations: 5
Reference
Elmadani M, Raatikainen S, Mattila O, Alakoski T, Piuhola J, xc5 str xf6 m P, et al. Dasatinib targets c-Src kinase in cardiotoxicity. Toxicol Rep. 2023;10:521-528 pubmed publisher
Lima N, Atkinson E, Bunney T, Katan M, Huang P. Targeting the Src Pathway Enhances the Efficacy of Selective FGFR Inhibitors in Urothelial Cancers with FGFR3 Alterations. Int J Mol Sci. 2020;21: pubmed publisher
Beadnell T, Nassar K, Rose M, Clark E, Danysh B, Hofmann M, et al. Src-mediated regulation of the PI3K pathway in advanced papillary and anaplastic thyroid cancer. Oncogenesis. 2018;7:23 pubmed publisher
Yeung C, Ngo V, Grohar P, Arnaldez F, Asante A, Wan X, et al. Loss-of-function screen in rhabdomyosarcoma identifies CRKL-YES as a critical signal for tumor growth. Oncogene. 2013;32:5429-38 pubmed publisher
Zhang X, Wang Q, Gerald W, Hudis C, Norton L, Smid M, et al. Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell. 2009;16:67-78 pubmed publisher
product information
Catalog Number :
26980
Product Name :
pBABE-Src-Dasatinib-resistant
article :
doi10.1016/j.ccr.2009.05.017
id3864
pubmed_id19573813
bacterial resistance :
Ampicillin
cloning :
backbonepBABE-hygro
backbone_mutation
backbone_originAddgene Plasmid 1765
backbone_size5558
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
growth notes :
Dasatinib resistant mutant. GenBank: V00402.1
origin :
37
pi :
alt_names
pp60-c-src
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BamHI
promoter
sequencing_primer_3pBABE-3
sequencing_primer_5pBABE-5
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesPP60C-SCR, SDR, c-src
geneSRC
id396442
genbank_ids
V00402
mutationT338I
namec-Src
shRNA_sequence
size1600
species
9031
Gallus gallus
tags
resistance markers :
313
tags :
High Copy
terms :
Hygromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA