This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMVTNT-T7-KPNA2
catalog :
26678
citations: 10
Reference
Wang H, Hu J, Yi K, Ma Z, Song X, Lee Y, et al. Dual control of formin-nucleated actin assembly by the chromatin and ER in mouse oocytes. Curr Biol. 2022;32:4013-4024.e6 pubmed publisher
Yang T, Li T, Huang R, Pan M, Lin S, Lin S, et al. Tumor suppressor BAP1 nuclear import is governed by transportin-1. J Cell Biol. 2022;221: pubmed publisher
Wang Y, Liu R, Liao J, Jiang L, Jeong G, Zhou L, et al. Orthogonal ubiquitin transfer reveals human papillomavirus E6 downregulates nuclear transport to disarm interferon-γ dependent apoptosis of cervical cancer cells. FASEB J. 2021;35:e21986 pubmed publisher
Hancock M, Meyer R, Mistry M, Khetani R, Wagschal A, Shin T, et al. Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression. Cell. 2019;177:722-736.e22 pubmed publisher
Myat A, Ogawa T, Kadota Watanabe C, Moriyama K. Nuclear import of transcriptional corepressor BCOR occurs through interaction with karyopherin α expressed in human periodontal ligament. Biochem Biophys Res Commun. 2018;507:67-73 pubmed publisher
Fu Y, Long M, Wisitpitthaya S, Inayat H, Pierpont T, Elsaid I, et al. Nuclear RNR-α antagonizes cell proliferation by directly inhibiting ZRANB3. Nat Chem Biol. 2018;14:943-954 pubmed publisher
von Morgen P, Lidak T, Horejsi Z, Macurek L. Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal. Biol Cell. 2018;110:137-146 pubmed publisher
Kapinos L, Huang B, Rencurel C, Lim R. Karyopherins regulate nuclear pore complex barrier and transport function. J Cell Biol. 2017;216:3609-3624 pubmed publisher
Hwang B, McCool K, Wan J, Wuerzberger Davis S, Young E, Choi E, et al. IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation. J Biol Chem. 2015;290:17967-84 pubmed publisher
Kelley J, Talley A, Spencer A, Gioeli D, Paschal B. Karyopherin alpha7 (KPNA7), a divergent member of the importin alpha family of nuclear import receptors. BMC Cell Biol. 2010;11:63 pubmed publisher
product information
Catalog Number :
26678
Product Name :
pCMVTNT-T7-KPNA2
article :
doi10.1186/1471-2121-11-63
id3739
pubmed_id20701745
bacterial resistance :
Ampicillin
cloning :
backbonepCMVTNT
backbone_mutation
backbone_originPromega
backbone_size4050
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
KPNA 2
Importin Alpha 1
cloning
clone_methodRestriction Enzyme
cloning_site_3SmaI
cloning_site_5EcoRI
promoter
sequencing_primer_3SV40 late poly A
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesIPOA1, PTAC58, QIP2, RCH1, SRP1-alpha, SRP1alpha
geneKPNA2
id3838
genbank_ids
NM_002266
mutation
nameKaryopherin Alpha 2
shRNA_sequence
size1590
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagT7 (MASMTGGQQMG)
resistance markers :
827
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA