This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pSIH1-puro-STAT3 shRNA
catalog :
26596
citations: 13
Reference
Yanagimura N, Takeuchi S, Fukuda K, Arai S, Tanimoto A, Nishiyama A, et al. STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis. NPJ Precis Oncol. 2022;6:11 pubmed publisher
Wright G, Sonavane M, Gassman N. Activated STAT3 Is a Novel Regulator of the XRCC1 Promoter and Selectively Increases XRCC1 Protein Levels in Triple Negative Breast Cancer. Int J Mol Sci. 2021;22: pubmed publisher
Ranjan A, Kaushik I, Srivastava S. Pimozide Suppresses the Growth of Brain Tumors by Targeting STAT3-Mediated Autophagy. Cells. 2020;9: pubmed publisher
Dutta P, Zhang L, Zhang H, Peng Q, Montgrain P, Wang Y, et al. Unphosphorylated STAT3 in heterochromatin formation and tumor suppression in lung cancer. BMC Cancer. 2020;20:145 pubmed publisher
Yi L, Chen L, Guo X, Lu T, Wang H, Ji X, et al. A Synthetic Disaccharide Derivative of Diphyllin, TAARD, Activates Human Natural Killer Cells to Secrete Interferon-Gamma via Toll-Like Receptor-Mediated NF-κB and STAT3 Signaling Pathways. Front Immunol. 2018;9:1509 pubmed publisher
Lim R, Li L, Yong E, Chew N. STAT-3 regulation of CXCR4 is necessary for the prenylflavonoid Icaritin to enhance mesenchymal stem cell proliferation, migration and osteogenic differentiation. Biochim Biophys Acta Gen Subj. 2018;1862:1680-1692 pubmed publisher
Lim R, Li L, Chew N, Yong E. The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression. Bone. 2017;105:122-133 pubmed publisher
Huang T, Alvarez A, Pangeni R, Horbinski C, Lu S, Kim S, et al. A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways. Nat Commun. 2016;7:12885 pubmed publisher
Teng Y, Pi W, Wang Y, Cowell J. WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling. Oncogene. 2016;35:4633-40 pubmed publisher
Choi Y, Cho S, Woo S, Yun Y, Park S, Shin Y, et al. Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling. Mediators Inflamm. 2014;2014:492173 pubmed publisher
Teng Y, Ghoshal P, Ngoka L, Mei Y, Cowell J. Critical role of the WASF3 gene in JAK2/STAT3 regulation of cancer cell motility. Carcinogenesis. 2013;34:1994-9 pubmed publisher
Lupberger J, Duong F, Fofana I, Zona L, Xiao F, Thumann C, et al. Epidermal growth factor receptor signaling impairs the antiviral activity of interferon-alpha. Hepatology. 2013;58:1225-35 pubmed publisher
Huang S, Sinicrope F. Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. Mol Cancer Ther. 2010;9:742-50 pubmed publisher
product information
Catalog Number :
26596
Product Name :
pSIH1-puro-STAT3 shRNA
article :
doi10.1158/1535-7163.MCT-09-1004
id3707
pubmed_id20197401
bacterial resistance :
Ampicillin
cloning :
backbonepSIH1-H1-puro
backbone_mutation
backbone_originSystem Biosciences
backbone_size7200
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Lentiviral
RNAi
growth notes :
gatccGCATCTGCCTAGATCGGCTATTCAAGAGATAGCC
GATCTAGGCAGATGTTTTTTg
STAT3 shRNA sequence:
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5BamHI
promoter
sequencing_primer_3
sequencing_primer_5agtgtcactaggcgggaacac
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADMIO, ADMIO1, APRF, HIES
geneSTAT3
id6774
genbank_ids
mutation
nameSTAT3 shRNA
shRNA_sequence
size60
species
9606
Homo sapiens
tags
resistance markers :
815
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA