This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Cav2.2e[ a10, 18a, 24a, 31a, 37b, 46]
catalog :
26571
citations: 4
Reference
Castro Junior C, Gomez M, Borges M, Lipscombe D, Andrade A. ω-Phonetoxins inhibit voltage-gated calcium CaV2.2 ion channel splice isoforms of dorsal root ganglia. bioRxiv. 2023;: pubmed publisher
Bunda A, LaCarubba B, Bertolino M, Akiki M, Bath K, Lopez Soto J, et al. Cacna1b alternative splicing impacts excitatory neurotransmission and is linked to behavioral responses to aversive stimuli. Mol Brain. 2019;12:81 pubmed publisher
Ruchala I, Cabra V, Solis E, Glennon R, De Felice L, Eltit J. Electrical coupling between the human serotonin transporter and voltage-gated Ca(2+) channels. Cell Calcium. 2014;56:25-33 pubmed publisher
Lin Z, Haus S, Edgerton J, Lipscombe D. Identification of functionally distinct isoforms of the N-type Ca2+ channel in rat sympathetic ganglia and brain. Neuron. 1997;18:153-66 pubmed
product information
Catalog Number :
26571
Product Name :
Cav2.2e[ a10, 18a, 24a, 31a, 37b, 46]
article :
doi10.1016/S0896-6273(01)80054-4
id3693
pubmed_id9010213
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA6/V5-His ABC
backbone_mutation
backbone_originInvitrogen
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Isolated from superior cervical ganglia. For more information about this plasmid: http://neuroscience.brown.edu/LipscombeLab/homepage/otherpages/clonespage/clonespage1.htm Also see: GENBANK AF222337
growth temp :
Top10F'
inserts :
Top10F'
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcorV
cloning_site_5KpnI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBIII
geneCacna1b
id257648
genbank_ids
AF055477
mutationDeletion of exons a10, 18a, and 31a Contains exons 24a, 37b and 46.
namecalcium channel alpha-1B subunit
shRNA_sequence
size7390
species
10116
Rattus norvegicus
tags
locationC terminal on backbone
tagV5
locationC terminal on backbone
tag6XHis
resistance markers :
813
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA