This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pRK-ATF4
catalog :
26114
citations: 14
Reference
Du L, Yang H, Ren Y, Ding Y, Xu Y, Zi X, et al. Inhibition of LSD1 induces ferroptosis through the ATF4-xCT pathway and shows enhanced anti-tumor effects with ferroptosis inducers in NSCLC. Cell Death Dis. 2023;14:716 pubmed publisher
Gouveia Roque C, Chung K, McCurdy E, Jagannathan R, Randolph L, Herline Killian K, et al. CREB3L2-ATF4 heterodimerization defines a transcriptional hub of Alzheimer's disease gene expression linked to neuropathology. Sci Adv. 2023;9:eadd2671 pubmed publisher
Zhang Y, Huynh Dam K, Ding X, Sikirzhytski V, Lim C, Broude E, et al. RASSF1 is identified by transcriptome coordination analysis as a target of ATF4. FEBS Open Bio. 2023;13:556-569 pubmed publisher
Yamada Y, Saito H, Araki M, Tsuchimoto Y, Muroi S, Suzuki K, et al. Wogonin, a Compound in Scutellaria baicalensis, Activates ATF4-FGF21 Signaling in Mouse Hepatocyte AML12 Cells. Nutrients. 2022;14: pubmed publisher
Ha D, Lee A. Insulin-like growth factor 1-receptor signaling stimulates GRP78 expression through the PI3K/AKT/mTOR/ATF4 axis. Cell Signal. 2020;75:109736 pubmed publisher
Jeong M, Jeong H, Ahn B, Pyun J, Kwon I, Cho H, et al. PRMT1 suppresses ATF4-mediated endoplasmic reticulum response in cardiomyocytes. Cell Death Dis. 2019;10:903 pubmed publisher
Hitzel J, Lee E, Zhang Y, Bibli S, Li X, Zukunft S, et al. Oxidized phospholipids regulate amino acid metabolism through MTHFD2 to facilitate nucleotide release in endothelial cells. Nat Commun. 2018;9:2292 pubmed publisher
Linares J, Cordes T, Duran A, Reina Campos M, Valencia T, Ahn C, et al. ATF4-Induced Metabolic Reprograming Is a Synthetic Vulnerability of the p62-Deficient Tumor Stroma. Cell Metab. 2017;26:817-829.e6 pubmed publisher
Masuda M, Miyazaki Anzai S, Keenan A, Shiozaki Y, Okamura K, Chick W, et al. Activating transcription factor-4 promotes mineralization in vascular smooth muscle cells. JCI Insight. 2016;1:e88646 pubmed publisher
Cagalinec M, Liiv M, Hodurova Z, Hickey M, Vaarmann A, Mandel M, et al. Role of Mitochondrial Dynamics in Neuronal Development: Mechanism for Wolfram Syndrome. PLoS Biol. 2016;14:e1002511 pubmed publisher
Gupta A, Hossain M, Miller N, Kerin M, Callagy G, Gupta S. NCOA3 coactivator is a transcriptional target of XBP1 and regulates PERK-eIF2α-ATF4 signalling in breast cancer. Oncogene. 2016;35:5860-5871 pubmed publisher
Gowen B, Chim B, Marceau C, Greene T, Burr P, Gonzalez J, et al. A forward genetic screen reveals novel independent regulators of ULBP1, an activating ligand for natural killer cells. elife. 2015;4: pubmed publisher
De Sousa Coelho A, Marrero P, Haro D. Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation. Biochem J. 2012;443:165-71 pubmed publisher
Wang Q, Mora Jensen H, Weniger M, Perez Galan P, Wolford C, Hai T, et al. ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proc Natl Acad Sci U S A. 2009;106:2200-5 pubmed publisher
product information
Catalog Number :
26114
Product Name :
pRK-ATF4
article :
doi10.1073/pnas.0807611106
id3613
pubmed_id19164757
bacterial resistance :
Ampicillin
cloning :
backbonepRK5-A20 (TNFAIP3)
backbone_mutation
backbone_originDr. Hongbin Shu
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5SalI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5unknown
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCREB-2, CREB2, TAXREB67, TXREB
geneATF4
id468
genbank_ids
mutation
nameATF4
shRNA_sequence
size1050
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagFLAG
resistance markers :
835
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA