This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
PGL3-NOXA-N1
catalog :
26112
citations: 3
Reference
Li W, Yu X, Xia Z, Yu X, Xie L, Ma X, et al. Repression of Noxa by Bmi1 contributes to deguelin-induced apoptosis in non-small cell lung cancer cells. J Cell Mol Med. 2018;22:6213-6227 pubmed publisher
Escobar D, Hepp M, Farkas C, Campos T, Sodir N, Morales M, et al. Sall2 is required for proapoptotic Noxa expression and genotoxic stress-induced apoptosis by doxorubicin. Cell Death Dis. 2015;6:e1816 pubmed publisher
Wang Q, Mora Jensen H, Weniger M, Perez Galan P, Wolford C, Hai T, et al. ERAD inhibitors integrate ER stress with an epigenetic mechanism to activate BH3-only protein NOXA in cancer cells. Proc Natl Acad Sci U S A. 2009;106:2200-5 pubmed publisher
product information
Catalog Number :
26112
Product Name :
PGL3-NOXA-N1
article :
doi10.1073/pnas.0807611106
id3613
pubmed_id19164757
bacterial resistance :
Ampicillin
cloning :
backbonepGL3
backbone_mutation
backbone_origin
backbone_size5000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
origin :
37
pi :
alt_names
NOXA promoter N1
PMAIP1
cloning
clone_methodRestriction Enzyme
cloning_site_3BglII
cloning_site_5SacI
promoter
sequencing_primer_3
sequencing_primer_5CGAGCTC TCGGGAGCGTGTCCGGGCA
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPR, NOXA
genePMAIP1
id5366
genbank_ids
NM_021127
mutation
nameNOXA N1
shRNA_sequence
size243
species
9606
Homo sapiens
tags
resistance markers :
835
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA