This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
LZRS-HOTAIR
catalog :
26110
citations: 20
Reference
Chu D, Jin Y, Wang B, Jiao Y, Zhang C, Guo Z, et al. LncRNA HOTAIR Enhances Epithelial-to-mesenchymal Transition to Promote the Migration and Invasion of Liver Cancer by Regulating NUAK1 via Epigenetic Inhibition miR-145-5p Expression. J Cancer. 2023;14:2329-2343 pubmed publisher
Kuo F, Wang Y, Liu C, Li Y, Lu C, Su S, et al. LncRNA HOTAIR impairs the prognosis of papillary thyroid cancer via regulating cellular malignancy and epigenetically suppressing DLX1. Cancer Cell Int. 2022;22:396 pubmed publisher
Kuo F, Huang Y, Yen M, Lee C, Hsu K, Yang H, et al. Aberrant overexpression of HOTAIR inhibits abdominal adipogenesis through remodelling of genome-wide DNA methylation and transcription. Mol Metab. 2022;60:101473 pubmed publisher
Abba M, Fabre M, Lee J, Tatineni P, Kil H, Aldaz C. HOTAIR Modulated Pathways in Early-Stage Breast Cancer Progression. Front Oncol. 2021;11:783211 pubmed publisher
Abzhanova A, Hirschi A, Reiter N. An exon-biased biophysical approach and NMR spectroscopy define the secondary structure of a conserved helical element within the HOTAIR long non-coding RNA. J Struct Biol. 2021;213:107728 pubmed publisher
Chang C, Tseng C, Lai M, Chiang A, Lo L, Chen C, et al. Genetic impacts on thermostability of onco-lncRNA HOTAIR during the development and progression of endometriosis. PLoS ONE. 2021;16:e0248168 pubmed publisher
Seo S, Yoon J, Byun H, Lee S. HOTAIR Induces Methylation of PCDH10, a Tumor Suppressor Gene, by Regulating DNMT1 and Sponging with miR-148b in Gastric Adenocarcinoma. Yonsei Med J. 2021;62:118-128 pubmed publisher
Wang Y, Liu L, Hung Y, Chen C, Lin Y, Wu W, et al. Long non-coding RNA HOTAIR in circulatory exosomes is correlated with ErbB2/HER2 positivity in breast cancer. Breast. 2019;46:64-69 pubmed publisher
Liu L, Wang Y, Lin P, Zhang X, Cheng W, Liu S, et al. Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15. Int J Cancer. 2019;: pubmed publisher
Tian F, He X, Wang J, Li X, Ma X, Wu F, et al. Elevated Tristetraprolin Impairs Trophoblast Invasion in Women with Recurrent Miscarriage by Destabilization of HOTAIR. Mol Ther Nucleic Acids. 2018;12:600-609 pubmed publisher
Sun S, Wu Y, Guo W, Yu F, Kong L, Ren Y, et al. STAT3/HOTAIR Signaling Axis Regulates HNSCC Growth in an EZH2-dependent Manner. Clin Cancer Res. 2018;24:2665-2677 pubmed publisher
Zhang Y, Jin F, Li X, Shen F, Ma X, Wu F, et al. The YY1-HOTAIR-MMP2 Signaling Axis Controls Trophoblast Invasion at the Maternal-Fetal Interface. Mol Ther. 2017;25:2394-2403 pubmed publisher
Özeş A, Wang Y, Zong X, Fang F, Pilrose J, Nephew K. Therapeutic targeting using tumor specific peptides inhibits long non-coding RNA HOTAIR activity in ovarian and breast cancer. Sci Rep. 2017;7:894 pubmed publisher
Portoso M, Ragazzini R, Brenčič Ž, Moiani A, Michaud A, Vassilev I, et al. PRC2 is dispensable for HOTAIR-mediated transcriptional repression. EMBO J. 2017;36:981-994 pubmed publisher
Zhai N, Xia Y, Yin R, Liu J, Gao F. A negative regulation loop of long noncoding RNA HOTAIR and p53 in non-small-cell lung cancer. Onco Targets Ther. 2016;9:5713-5720 pubmed
Lee N, Lee J, Kim W, Yun S, Youn Y, Park C, et al. Promoter methylation of PCDH10 by HOTAIR regulates the progression of gastrointestinal stromal tumors. Oncotarget. 2016;7:75307-75318 pubmed publisher
Kalwa M, Hänzelmann S, Otto S, Kuo C, Franzen J, Joussen S, et al. The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation. Nucleic Acids Res. 2016;44:10631-10643 pubmed
Özeş A, Miller D, Ozes O, Fang F, Liu Y, Matei D, et al. NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer. Oncogene. 2016;35:5350-5361 pubmed publisher
Davidovich C, Goodrich K, Gooding A, Cech T. A dimeric state for PRC2. Nucleic Acids Res. 2014;42:9236-48 pubmed publisher
Gupta R, Shah N, Wang K, Kim J, Horlings H, Wong D, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010;464:1071-6 pubmed publisher
product information
Catalog Number :
26110
Product Name :
LZRS-HOTAIR
article :
doi10.1038/nature08975
id3612
pubmed_id20393566
bacterial resistance :
Ampicillin
cloning :
backboneLZRS
backbone_mutation
backbone_origin
backbone_size11100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Retroviral
growth temp :
STBL2
origin :
37
pi :
alt_names
cloning
clone_methodGateway Cloning
cloning_site_3attR
cloning_site_5attR
promoter
sequencing_primer_3ATCGTCGACCACTGTGCTGG
sequencing_primer_5TGGATACACGCCGCCCACGTG
site_3_destroyed1
site_5_destroyed1
entrez_gene
aliasesHOXAS, HOXC-AS4, HOXC11-AS1, NCRNA00072
geneHOTAIR
id100124700
genbank_ids
mutation
nameHOTAIR
shRNA_sequence
size2146
species
9606
Homo sapiens
tags
resistance markers :
792
tags :
Low Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA