This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
YFP-NavII-III
catalog :
26056
citations: 6
Reference
Tjiang N, Zempel H. A mitochondria cluster at the proximal axon initial segment controls axodendritic TAU trafficking in rodent primary and human iPSC-derived neurons. Cell Mol Life Sci. 2022;79:120 pubmed publisher
Evans C, Holzbaur E. Degradation of engulfed mitochondria is rate-limiting in Optineurin-mediated mitophagy in neurons. elife. 2020;9: pubmed publisher
Emperador Melero J, Huson V, Van Weering J, Bollmann C, Fischer von Mollard G, Toonen R, et al. Vti1a/b regulate synaptic vesicle and dense core vesicle secretion via protein sorting at the Golgi. Nat Commun. 2018;9:3421 pubmed publisher
Dumitrescu A, Evans M, Grubb M. Evaluating Tools for Live Imaging of Structural Plasticity at the Axon Initial Segment. Front Cell Neurosci. 2016;10:268 pubmed
Maday S, Holzbaur E. Compartment-Specific Regulation of Autophagy in Primary Neurons. J Neurosci. 2016;36:5933-45 pubmed publisher
Grubb M, Burrone J. Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability. Nature. 2010;465:1070-4 pubmed publisher
product information
Catalog Number :
26056
Product Name :
YFP-NavII-III
article :
doi10.1038/nature09160
id3553
pubmed_id20543823
bacterial resistance :
Kanamycin
cloning :
backbonepEYFP-N1
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
sodium channel subunit Nav1.2
sodium channel, voltage-gated
cloning
clone_methodRestriction Enzyme
cloning_site_3BsrGI
cloning_site_5BsrGI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesNachII, Nav1.2, RII/RIIA, RNSCPIIR, SCN, Scn2a1, Scn2a2, ScpII
geneScn2a
id24766
genbank_ids
mutationThe insert codes only for the intracellular loop between transmembrane domains II and III
nameNav1.2
shRNA_sequence
size684
species
10116
Rattus norvegicus
tags
locationN terminal on backbone
tagYFP
resistance markers :
788
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA