This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLKO-RB1-shRNA63
catalog :
25641
citations: 6
Reference
Davies A, Nouruzi S, Ganguli D, Namekawa T, Thaper D, Linder S, et al. An androgen receptor switch underlies lineage infidelity in treatment-resistant prostate cancer. Nat Cell Biol. 2021;23:1023-1034 pubmed publisher
Klein F, Granier C, Zhao Y, Pan Q, Tong Z, Gschwend J, et al. Combination of Talazoparib and Palbociclib as a Potent Treatment Strategy in Bladder Cancer. J Pers Med. 2021;11: pubmed publisher
Wu Q, Ba Alawi W, Deblois G, Cruickshank J, Duan S, Lima Fernandes E, et al. GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer. Nat Commun. 2020;11:4205 pubmed publisher
Kim K, Godarova A, Seedle K, Kim M, Ince T, Wells S, et al. Rb suppresses collective invasion, circulation and metastasis of breast cancer cells in CD44-dependent manner. PLoS ONE. 2013;8:e80590 pubmed publisher
Cheng Z, Gong Y, Ma Y, Lu K, Lu X, Pierce L, et al. Inhibition of BET bromodomain targets genetically diverse glioblastoma. Clin Cancer Res. 2013;19:1748-59 pubmed publisher
Michaud K, Solomon D, Oermann E, Kim J, Zhong W, Prados M, et al. Pharmacologic inhibition of cyclin-dependent kinases 4 and 6 arrests the growth of glioblastoma multiforme intracranial xenografts. Cancer Res. 2010;70:3228-38 pubmed publisher
product information
Catalog Number :
25641
Product Name :
pLKO-RB1-shRNA63
article :
doi10.1158/0008-5472.CAN-09-4559
id3465
pubmed_id20354191
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1 puro
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
growth strain :
3rd generation lentiviral vector
origin :
37
pi :
alt_names
Retinoblastoma tumor susceptibility protein
RB1
Rb
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesOSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
geneRB1
id5925
genbank_ids
NM_000321
mutation
nameRB1-shRNA 63
shRNA_sequence
size42
species
9606
Homo sapiens
tags
plasmid copy :
The RNAi Consortium (TRC), MISSION shRNA
resistance markers :
757
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA