This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLKO-PTEN-shRNA-3001
catalog :
25639
citations: 4
Reference
Li Q, Jiang B, Guo J, Shao H, Del Priore I, Chang Q, et al. INK4 tumor suppressor proteins mediate resistance to CDK4/6 kinase inhibitors. Cancer Discov. 2021;: pubmed publisher
Hu C, Zhou H, Liu Y, Huang J, Liu W, Zhang Q, et al. ROCK1 promotes migration and invasion of non‑small‑cell lung cancer cells through the PTEN/PI3K/FAK pathway. Int J Oncol. 2019;55:833-844 pubmed publisher
Zhao B, Shah P, Qiang L, He T, Budanov A, He Y. Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol. 2017;93:375-381 pubmed publisher
Kim J, Lee C, Bonifant C, Ressom H, Waldman T. Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. Mol Cell Biol. 2007;27:662-77 pubmed
product information
Catalog Number :
25639
Product Name :
pLKO-PTEN-shRNA-3001
article :
doi10.1128/MCB.00537-06
id3464
pubmed_id17060456
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1 puro
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
origin :
37
pi :
sapienstags
TEP1genePTEN
id5728<
/tr>>genbank_ids>
NM_000314
tr>mutation<
tr>namePTEN-shRNA-3001>shRNA_sequenceCC
GGCCACAAATGAAGGGATATAAACTCGAGTTTATATCCC
TTCATTTGTGGTTTTTsize<
/td>42species>
9606
Homo
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta,
plasmid copy :
The RNAi Consortium (TRC), MISSION shRNA
resistance markers :
757
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA