This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLKO-PTEN-shRNA-1320
catalog :
25638
citations: 7
Reference
Lu Y, Lin Q, Lin C, Chen J, Jiang X, He H. Down-regulation of miR-424 inhibited the metastasis of endometrial carcinoma via targeting PTEN/PI3K/AKT signaling pathway. J Cancer. 2023;14:2811-2819 pubmed publisher
Li Q, Jiang B, Guo J, Shao H, Del Priore I, Chang Q, et al. INK4 tumor suppressor proteins mediate resistance to CDK4/6 kinase inhibitors. Cancer Discov. 2021;: pubmed publisher
Wang Y, Wong C, Yan M, Li L, Liu T, Or P, et al. Differential regulation of the pro-inflammatory biomarker, YKL-40/CHI3L1, by PTEN/Phosphoinositide 3-kinase and JAK2/STAT3 pathways in glioblastoma. Cancer Lett. 2018;429:54-65 pubmed publisher
Zhao B, Shah P, Qiang L, He T, Budanov A, He Y. Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes. Photochem Photobiol. 2017;93:375-381 pubmed publisher
Zhang H, Cao H, Xu D, Zhu K. MicroRNA-92a promotes metastasis of nasopharyngeal carcinoma by targeting the PTEN/AKT pathway. Onco Targets Ther. 2016;9:3579-88 pubmed publisher
Chen J, Yan D, Wu W, Zhu J, Ye W, Shu Q. MicroRNA-130a promotes the metastasis and epithelial-mesenchymal transition of osteosarcoma by targeting PTEN. Oncol Rep. 2016;35:3285-92 pubmed publisher
Kim J, Lee C, Bonifant C, Ressom H, Waldman T. Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. Mol Cell Biol. 2007;27:662-77 pubmed
product information
Catalog Number :
25638
Product Name :
pLKO-PTEN-shRNA-1320
article :
doi10.1128/MCB.00537-06
id3464
pubmed_id17060456
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1 puro
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
origin :
37
pi :
sapienstags
TEP1genePTEN
id5728<
/tr>>genbank_ids>
nm_000314
tr>mutation<
tr>namePTEN-shRNA-1320>shRNA_sequenceCC
GGCCACAGCTAGAACTTATCAAACTCGAGTTTGATAAGT
TCTAGCTGTGGTTTTTsize<
/td>42species>
9606
Homo
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliases10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, PTENbeta,
plasmid copy :
The RNAi Consortium (TRC), MISSION shRNA
resistance markers :
757
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA