This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLKO-p53-shRNA-941
catalog :
25637
citations: 10
Reference
Romashin D, Rusanov A, Kozhin P, Karagyaur M, Tikhonova O, Zgoda V, et al. Impact of p53 knockdown on protein dataset of HaCaT cells. Data Brief. 2022;42:108274 pubmed publisher
Florian A, Woodley C, Wang J, Grieb B, Slota M, Guerrazzi K, et al. Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells. NAR Cancer. 2022;4:zcac007 pubmed publisher
Singh N, Ramnarine V, Song J, Pandey R, Padi S, Nouri M, et al. The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancer. Nat Commun. 2021;12:7349 pubmed publisher
Bryan A, Wang J, Howard G, Guarnaccia A, Woodley C, Aho E, et al. WDR5 is a conserved regulator of protein synthesis gene expression. Nucleic Acids Res. 2020;48:2924-2941 pubmed publisher
Park D, Cheng J, Berrios C, Montero J, Cortes Cros M, Ferretti S, et al. Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response. Proc Natl Acad Sci U S A. 2019;116:1027-1032 pubmed publisher
Xu W, Li B, Guan X, Chung S, Wang Y, Yip Y, et al. Cancer cell-secreted IGF2 instigates fibroblasts and bone marrow-derived vascular progenitor cells to promote cancer progression. Nat Commun. 2017;8:14399 pubmed publisher
Kemp M, Sancar A. ATR Kinase Inhibition Protects Non-cycling Cells from the Lethal Effects of DNA Damage and Transcription Stress. J Biol Chem. 2016;291:9330-42 pubmed publisher
Lee G, Oh T, Um K, Yoon H, Son J, Kim B, et al. Small-molecule inhibitors of USP7 induce apoptosis through oxidative and endoplasmic reticulum stress in cancer cells. Biochem Biophys Res Commun. 2016;470:181-186 pubmed publisher
Duan L, Perez R, Hansen M, Gitelis S, Maki C. Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1. Cancer Biol Ther. 2014;15:1600-12 pubmed publisher
Kim J, Lee C, Bonifant C, Ressom H, Waldman T. Activation of p53-dependent growth suppression in human cells by mutations in PTEN or PIK3CA. Mol Cell Biol. 2007;27:662-77 pubmed
product information
Catalog Number :
25637
Product Name :
pLKO-p53-shRNA-941
article :
doi10.1128/MCB.00537-06
id3464
pubmed_id17060456
bacterial resistance :
Ampicillin
cloning :
backbonepLKO.1 puro
backbone_mutation
backbone_origin
backbone_size7032
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
RNAi
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5LKO.1 5'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
NM_000546
mutation
namep53-shRNA-941
shRNA_sequence
size42
species
9606
Homo sapiens
tags
plasmid copy :
The RNAi Consortium (TRC), MISSION shRNA
resistance markers :
757
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA