This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
SIRT5
catalog :
25487
citations: 4
Reference
Yuan T, Kumar S, Skinner M, Victor Joseph R, Abuaita M, Keijer J, et al. SIRT5 variants from patients with mitochondrial disease are associated with reduced SIRT5 stability and activity, but not with neuropathology. bioRxiv. 2023;: pubmed publisher
Yuan T, Keijer J, Guo A, Lombard D, de Boer V. An optimized desuccinylase activity assay reveals a difference in desuccinylation activity between proliferative and differentiated cells. Sci Rep. 2020;10:17030 pubmed publisher
Xie Y, Ge J, Lei H, Peng B, Zhang H, Wang D, et al. Fluorescent Probes for Single-Step Detection and Proteomic Profiling of Histone Deacetylases. J Am Chem Soc. 2016;138:15596-15604 pubmed
Zhang Y, Bharathi S, Rardin M, Uppala R, Verdin E, Gibson B, et al. SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase. PLoS ONE. 2015;10:e0122297 pubmed publisher
product information
Catalog Number :
25487
Product Name :
SIRT5
article :
doi
id3425
pubmed_id
bacterial resistance :
Kanamycin
cloning :
backbonepET28a-LIC
backbone_mutation
backbone_originSGC
backbone_size7328
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth notes :
PDB ID: 2B4Y, 2NYR (supersedes 2FZQ) https://www.rcsb.org/structure/2NYR SGC links: https://www.thesgc.org/structures/2B4Y/ https://www.thesgc.org/structures/2NYR/
growth strain :
Bacterial expression for structure determination; may not be full ORF
origin :
37
pi :
alt_names
PDB ID: 2B4Y, 2NYR (supersedes 2FZQ)
Sirtuin 5 isoform 1
SIR2L5
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3T7-term
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSIR2L5
geneSIRT5
id23408
genbank_ids
mutation
nameSIRT5
shRNA_sequence
size807
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHis
resistance markers :
732
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA