This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
EF.STAT3DN.Ubc.GFP
catalog :
24984
citations: 14
Reference
Kim H, Leng K, Park J, Sorets A, Kim S, Shostak A, et al. Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin. Nat Commun. 2022;13:6581 pubmed publisher
Hansen L, Yang R, Roso K, Wang W, Chen L, Yang Q, et al. MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization. Sci Rep. 2022;12:4183 pubmed publisher
Mo M, Tong S, Yin H, Jin Z, Zu X, Hu X. SHCBP1 regulates STAT3/c-Myc signaling activation to promote tumor progression in penile cancer. Am J Cancer Res. 2020;10:3138-3156 pubmed
Im J, Kim B, Lee K, Chun S, Kang M, Won M. DDIAS promotes STAT3 activation by preventing STAT3 recruitment to PTPRM in lung cancer cells. Oncogenesis. 2020;9:1 pubmed publisher
Sun H, Yang W, Tian Y, Zeng X, Zhou J, Mok M, et al. An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. Nat Commun. 2018;9:5214 pubmed publisher
Tzeng Y, Liu P, Li J, Liu L, Kuo S, Hsieh C, et al. Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells. Front Pharmacol. 2018;9:1285 pubmed publisher
Morgan E, Wasson C, Hanson L, Kealy D, Pentland I, McGuire V, et al. STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle. PLoS Pathog. 2018;14:e1006975 pubmed publisher
Kim E, Jung J, Kim A, Chang Y, Kim S. ABT-737 Synergizes with Cisplatin Bypassing Aberration of Apoptotic Pathway in Non-small Cell Lung Cancer. Neoplasia. 2017;19:354-363 pubmed publisher
Gaviglio A, Knelson E, Blobe G. Heparin-binding epidermal growth factor-like growth factor promotes neuroblastoma differentiation. FASEB J. 2017;31:1903-1915 pubmed publisher
van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher
Nowak D, Cho H, Herzka T, Watrud K, DeMarco D, Wang V, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov. 2015;5:636-51 pubmed publisher
Choi Y, Cho S, Woo S, Yun Y, Park S, Shin Y, et al. Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling. Mediators Inflamm. 2014;2014:492173 pubmed publisher
Teng Y, Ghoshal P, Ngoka L, Mei Y, Cowell J. Critical role of the WASF3 gene in JAK2/STAT3 regulation of cancer cell motility. Carcinogenesis. 2013;34:1994-9 pubmed publisher
Hillion J, Dhara S, Sumter T, Mukherjee M, Di Cello F, Belton A, et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?. Cancer Res. 2008;68:10121-7 pubmed publisher
product information
Catalog Number :
24984
Product Name :
EF.STAT3DN.Ubc.GFP
article :
doi10.1158/0008-5472.CAN-08-2121
id3401
pubmed_id19074878
bacterial resistance :
Ampicillin
cloning :
backbonecFUGW
backbone_mutation
backbone_origin
backbone_size11500
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth temp :
Stbl 3
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5PacI
promoter
sequencing_primer_3hUBCpro-R
sequencing_primer_5EF1a-forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesADMIO, ADMIO1, APRF, HIES
geneSTAT3
id6774
genbank_ids
mutationY705F--dominant negative
nameSTAT3
shRNA_sequence
size2300
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFLAG
resistance markers :
76
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA