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Kunhiraman H, McSwain L, Shahab S, Gershon T, Macdonald T, Kenney A. IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma. Acta Neuropathol Commun. 2023;11:62 pubmed publisher

Zhao Q, Kohut A, LI Y, Martincuks A, Austria T, Zhang C, et al. Niraparib-induced STAT3 inhibition increases its antitumor effects. Front Oncol. 2022;12:966492 pubmed publisher

Ko M, Makena M, Schiapparelli P, Suárez Meade P, Mekile A, Lal B, et al. The endosomal pH regulator NHE9 is a driver of stemness in glioblastoma. PNAS Nexus. 2022;1:pgac013 pubmed publisher

Fisher M, Balinth S, Hwangbo Y, Wu C, Ballon C, Wilkinson J, et al. BRD4 Regulates Transcription Factor ΔNp63α to Drive a Cancer Stem Cell Phenotype in Squamous Cell Carcinomas. Cancer Res. 2021;81:6246-6258 pubmed publisher

Wang L, Astone M, Alam S, Zhu Z, Pei W, Frank D, et al. Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability. Dis Model Mech. 2021;14: pubmed publisher

Nalairndran G, Chung I, Abdul Razack A, Chung F, Hii L, Lim W, et al. Inhibition of Janus Kinase 1 synergizes docetaxel sensitivity in prostate cancer cells. J Cell Mol Med. 2021;: pubmed publisher

Mo M, Tong S, Yin H, Jin Z, Zu X, Hu X. SHCBP1 regulates STAT3/c-Myc signaling activation to promote tumor progression in penile cancer. Am J Cancer Res. 2020;10:3138-3156 pubmed

Wang L, Astone M, Alam S, Zhu Z, Pei W, Frank D, et al. Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability. bioRxiv. 2020;: pubmed publisher

Ma X, Wu K, Xu A, Jiao P, Li H, Xing L. The sesquiterpene lactone eupatolide induces apoptosis in non-small cell lung cancer cells by suppressing STAT3 signaling. Environ Toxicol Pharmacol. 2021;81:103513 pubmed publisher

Zhang C, Wang N, Tan H, Guo W, Chen F, Zhong Z, et al. Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF-1α-independent VEGF expression and angiogenesis in hepatocellular carcinoma. Br J Pharmacol. 2020;177:3240-3257 pubmed publisher

Ji X, He M. Sodium cantharidate targets STAT3 and abrogates EGFR inhibitor resistance in osteosarcoma. Aging (Albany NY). 2019;11:5848-5863 pubmed publisher

Li J, Huang Y, Kuo Y, Cheng C, Kuan F, Chang S, et al. Flavopereirine Suppresses the Growth of Colorectal Cancer Cells through P53 Signaling Dependence. Cancers (Basel). 2019;11: pubmed publisher

Neel D, Allegakoen D, Olivas V, Mayekar M, Hemmati G, Chatterjee N, et al. Differential Subcellular Localization Regulates Oncogenic Signaling by ROS1 Kinase Fusion Proteins. Cancer Res. 2019;79:546-556 pubmed publisher

Sun H, Yang W, Tian Y, Zeng X, Zhou J, Mok M, et al. An inflammatory-CCRK circuitry drives mTORC1-dependent metabolic and immunosuppressive reprogramming in obesity-associated hepatocellular carcinoma. Nat Commun. 2018;9:5214 pubmed publisher

Tzeng Y, Liu P, Li J, Liu L, Kuo S, Hsieh C, et al. Kinome-Wide siRNA Screening Identifies Src-Enhanced Resistance of Chemotherapeutic Drugs in Triple-Negative Breast Cancer Cells. Front Pharmacol. 2018;9:1285 pubmed publisher

Keremu A, Aimaiti A, Liang Z, Zou X. Role of the HDAC6/STAT3 pathway in regulating PD-L1 expression in osteosarcoma cell lines. Cancer Chemother Pharmacol. 2019;83:255-264 pubmed publisher

Lim R, Li L, Yong E, Chew N. STAT-3 regulation of CXCR4 is necessary for the prenylflavonoid Icaritin to enhance mesenchymal stem cell proliferation, migration and osteogenic differentiation. Biochim Biophys Acta Gen Subj. 2018;1862:1680-1692 pubmed publisher

Choi Y, Cho S, Choi Y, Yun Y, Lee K, Lee K, et al. SH003 suppresses breast cancer growth by accumulating p62 in autolysosomes. Oncotarget. 2017;8:88386-88400 pubmed publisher

Lim R, Li L, Chew N, Yong E. The prenylflavonoid Icaritin enhances osteoblast proliferation and function by signal transducer and activator of transcription factor 3 (STAT-3) regulation of C-X-C chemokine receptor type 4 (CXCR4) expression. Bone. 2017;105:122-133 pubmed publisher

Bixel K, Saini U, Kumar Bid H, Fowler J, Riley M, Wanner R, et al. Targeting STAT3 by HO3867 induces apoptosis in ovarian clear cell carcinoma. Int J Cancer. 2017;141:1856-1866 pubmed publisher

Mao X, Cho M, Ellebrecht C, Mukherjee E, Payne A. Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes. JCI Insight. 2017;2: pubmed publisher

Wang S, Ho H, Lin J, Shieh J, Wu C. Simvastatin-induced cell cycle arrest through inhibition of STAT3/SKP2 axis and activation of AMPK to promote p27 and p21 accumulation in hepatocellular carcinoma cells. Cell Death Dis. 2017;8:e2626 pubmed publisher

Chuang C, Greenside P, Rogers Z, Brady J, Yang D, Ma R, et al. Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis. Nat Med. 2017;23:291-300 pubmed publisher

van Andel H, Ren Z, Koopmans I, Joosten S, Kocemba K, de Lau W, et al. Aberrantly expressed LGR4 empowers Wnt signaling in multiple myeloma by hijacking osteoblast-derived R-spondins. Proc Natl Acad Sci U S A. 2017;114:376-381 pubmed publisher

Rui L, Drennan A, Ceribelli M, Zhu F, Wright G, Huang D, et al. Epigenetic gene regulation by Janus kinase 1 in diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2016;113:E7260-E7267 pubmed

Xue J, Zhou A, Wu Y, Morris S, Lin K, Amin S, et al. miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis. Cancer Res. 2016;76:4293-304 pubmed publisher

Sun F, Zhang Z, Tan E, Lim Z, Li Y, Wang X, et al. Icaritin suppresses development of neuroendocrine differentiation of prostate cancer through inhibition of IL-6/STAT3 and Aurora kinase A pathways in TRAMP mice. Carcinogenesis. 2016;37:701-711 pubmed publisher

Tiong K, Tan B, Choo H, Chung F, Hii L, Tan S, et al. Fibroblast growth factor receptor 4 (FGFR4) and fibroblast growth factor 19 (FGF19) autocrine enhance breast cancer cells survival. Oncotarget. 2016;7:57633-57650 pubmed publisher

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Tyagi N, Marimuthu S, Bhardwaj A, Deshmukh S, Srivastava S, Singh A, et al. p-21 activated kinase 4 (PAK4) maintains stem cell-like phenotypes in pancreatic cancer cells through activation of STAT3 signaling. Cancer Lett. 2016;370:260-7 pubmed publisher

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Hrustanovic G, Olivas V, Pazarentzos E, Tulpule A, Asthana S, Blakely C, et al. RAS-MAPK dependence underlies a rational polytherapy strategy in EML4-ALK-positive lung cancer. Nat Med. 2015;21:1038-47 pubmed publisher

Cao W, Liu Y, Zhang R, Zhang B, Wang T, Zhu X, et al. Homoharringtonine induces apoptosis and inhibits STAT3 via IL-6/JAK1/STAT3 signal pathway in Gefitinib-resistant lung cancer cells. Sci Rep. 2015;5:8477 pubmed publisher

Nowak D, Cho H, Herzka T, Watrud K, DeMarco D, Wang V, et al. MYC Drives Pten/Trp53-Deficient Proliferation and Metastasis due to IL6 Secretion and AKT Suppression via PHLPP2. Cancer Discov. 2015;5:636-51 pubmed publisher

Choi Y, Cho S, Woo S, Yun Y, Park S, Shin Y, et al. Herbal extract SH003 suppresses tumor growth and metastasis of MDA-MB-231 breast cancer cells by inhibiting STAT3-IL-6 signaling. Mediators Inflamm. 2014;2014:492173 pubmed publisher

Zhou Y, Tang Q, Zhao S, Zhang F, Li L, Wu W, et al. Targeting signal transducer and activator of transcription 3 contributes to the solamargine-inhibited growth and -induced apoptosis of human lung cancer cells. Tumour Biol. 2014;35:8169-78 pubmed publisher

Maycotte P, Gearheart C, Barnard R, Aryal S, Mulcahy Levy J, Fosmire S, et al. STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious. Cancer Res. 2014;74:2579-90 pubmed publisher

Datta A, Alexander R, Sulikowski M, Nicholson A, Maher T, Scotton C, et al. Evidence for a functional thymic stromal lymphopoietin signaling axis in fibrotic lung disease. J Immunol. 2013;191:4867-79 pubmed publisher

Hillion J, Dhara S, Sumter T, Mukherjee M, Di Cello F, Belton A, et al. The high-mobility group A1a/signal transducer and activator of transcription-3 axis: an achilles heel for hematopoietic malignancies?. Cancer Res. 2008;68:10121-7 pubmed publisher