This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCDNA-myc-HisA-Sirt3
catalog :
24924
citations: 3
Reference
Smolkova K, Špačková J, Gotvaldová K, Dvořák A, Křenková A, Hubalek M, et al. SIRT3 and GCN5L regulation of NADP+- and NADPH-driven reactions of mitochondrial isocitrate dehydrogenase IDH2. Sci Rep. 2020;10:8677 pubmed publisher
Palomer X, Román Azcona M, Pizarro Delgado J, Planavila A, Villarroya F, Valenzuela Alcaraz B, et al. SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation. Signal Transduct Target Ther. 2020;5:14 pubmed publisher
Ahn B, Kim H, Song S, Lee I, Liu J, Vassilopoulos A, et al. A role for the mitochondrial deacetylase Sirt3 in regulating energy homeostasis. Proc Natl Acad Sci U S A. 2008;105:14447-52 pubmed publisher
product information
Catalog Number :
24924
Product Name :
pCDNA-myc-HisA-Sirt3
article :
doi10.1073/pnas.0803790105
id3373
pubmed_id18794531
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA4/myc-His A
backbone_mutation
backbone_originInvitrogen
backbone_size5075
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
NB: This construct was not used in this paper. The construct used in this paper is the HisB version.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesSIR2L3
geneSIRT3
id23410
genbank_ids
mutation
nameSirt3
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationC terminal on insert
tagMyc
locationC terminal on insert
tagHis
resistance markers :
146
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA