This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV-myc-Atg5
catalog :
24922
citations: 11
Reference
Wu M, An R, Zhou N, Chen Y, Cai H, Yan Q, et al. Toxoplasma gondii CDPK3 Controls the Intracellular Proliferation of Parasites in Macrophages. Front Immunol. 2022;13:905142 pubmed publisher
Sun R, Hedl M, Abraham C. TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants. Cell Mol Gastroenterol Hepatol. 2021;11:249-272 pubmed publisher
Kang J, Yan J, Ranjan K, Zhang X, Turner J, Abraham C. Myeloid Cell Expression of LACC1 is Required for Bacterial Clearance and Control of Intestinal Inflammation. Gastroenterology. 2020;: pubmed publisher
Yu K, Xiang L, Li S, Wang S, Chen C, Mu H. HIF1α promotes prostate cancer progression by increasing ATG5 expression. Anim Cells Syst (Seoul). 2019;23:326-334 pubmed publisher
Hedl M, Yan J, Witt H, Abraham C. IRF5 Is Required for Bacterial Clearance in Human M1-Polarized Macrophages, and IRF5 Immune-Mediated Disease Risk Variants Modulate This Outcome. J Immunol. 2019;202:920-930 pubmed publisher
Wang L, Guo W, Ma J, Dai W, Liu L, Guo S, et al. Aberrant SIRT6 expression contributes to melanoma growth: Role of the autophagy paradox and IGF-AKT signaling. Autophagy. 2018;14:518-533 pubmed publisher
Yan J, Hedl M, Abraham C. An inflammatory bowel disease-risk variant in INAVA decreases pattern recognition receptor-induced outcomes. J Clin Invest. 2017;127:2192-2205 pubmed publisher
Kim M, Sandford E, Gatica D, Qiu Y, Liu X, Zheng Y, et al. Mutation in ATG5 reduces autophagy and leads to ataxia with developmental delay. elife. 2016;5: pubmed publisher
Zhao X, Fang Y, Yang Y, Qin Y, Wu P, Wang T, et al. Elaiophylin, a novel autophagy inhibitor, exerts antitumor activity as a single agent in ovarian cancer cells. Autophagy. 2015;11:1849-63 pubmed publisher
Zou M, Lu N, Hu C, Liu W, Sun Y, Wang X, et al. Beclin 1-mediated autophagy in hepatocellular carcinoma cells: implication in anticancer efficiency of oroxylin A via inhibition of mTOR signaling. Cell Signal. 2012;24:1722-32 pubmed publisher
Lee I, Cao L, Mostoslavsky R, Lombard D, Liu J, Bruns N, et al. A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy. Proc Natl Acad Sci U S A. 2008;105:3374-9 pubmed publisher
product information
Catalog Number :
24922
Product Name :
pCMV-myc-Atg5
article :
doi10.1073/pnas.0712145105
id3374
pubmed_id18296641
bacterial resistance :
Ampicillin
cloning :
backbonepCMV-Myc
backbone_mutation
backbone_originClontech
backbone_size3800
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5SalI
promoter
sequencing_primer_3EBV-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPG5, APG5-LIKE, APG5L, ASP, SCAR25, hAPG5
geneATG5
id9474
genbank_ids
BC002699
mutation
nameAtg5
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tagMyc
resistance markers :
146
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA