This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Gal4-HA-HIF1 (530-652)
catalog :
24887
citations: 5
Reference
Geng Q, Kong Y, Li W, Zhang J, Ma H, Zhang Y, et al. Dynamic Phosphorylation of G9a Regulates its Repressive Activity on Chromatin Accessibility and Mitotic Progression. Adv Sci (Weinh). 2023;10:e2303224 pubmed publisher
Zhang C, Gao Y, Jadhav U, Hung H, Holton K, Grodzinsky A, et al. Creb5 establishes the competence for Prg4 expression in articular cartilage. Commun Biol. 2021;4:332 pubmed publisher
Li Z, Wang B, Lv L, Tang T, Wen Y, Cao J, et al. FIH-1-modulated HIF-1α C-TAD promotes acute kidney injury to chronic kidney disease progression via regulating KLF5 signaling. Acta Pharmacol Sin. 2021;: pubmed publisher
Baumann B, Hayashida T, Liang X, Schnaper H. Hypoxia-inducible factor-1α promotes glomerulosclerosis and regulates COL1A2 expression through interactions with Smad3. Kidney Int. 2016;90:797-808 pubmed publisher
Ivan M, Kondo K, Yang H, Kim W, Valiando J, Ohh M, et al. HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing. Science. 2001;292:464-8 pubmed
product information
Catalog Number :
24887
Product Name :
Gal4-HA-HIF1 (530-652)
article :
doi10.1126/science.1059817
id3367
pubmed_id11292862
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA3
backbone_mutation
backbone_originInvitrogen
backbone_size5252
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth temp :
DH5alpha or similar
origin :
37
pi :
alt_names
Gal4-HA-HIF-ODD
oxygen-dependent degradation domain
cloning
clone_methodRestriction Enzyme
cloning_site_3Xba I
cloning_site_5Hind III
promoter
sequencing_primer_3Sp6
sequencing_primer_5CMV-forw or T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78
geneHIF1A
id3091
genbank_ids
mutationpartial HIF1alpha cDNA (encoding aa 530-652)fused to Gal4 DNA binding domain, fused to HA-tag
namehypoxia inducible factor1alpha
shRNA_sequence
size909
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGal4dbd
locationN terminal on backbone
tagHA-tag
resistance markers :
238
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA