This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
human p53-(94-312)
catalog :
24866
citations: 7
Reference
Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, et al. Intracellular FGF1 protects cells from apoptosis through direct interaction with p53. Cell Mol Life Sci. 2023;80:311 pubmed publisher
Lima I, Pedrote M, Marques M, Sousa G, Silva J, de Oliveira G, et al. Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain. Biochemistry. 2023;62:35-43 pubmed publisher
Navalkar A, Paul A, Sakunthala A, Pandey S, Dey A, Saha S, et al. Oncogenic gain of function due to p53 amyloids by aberrant alteration of cell cycle and proliferation. J Cell Sci. 2022;: pubmed publisher
Petronilho E, Pedrote M, Marques M, Passos Y, Mota M, Jakobus B, et al. Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands. Chem Sci. 2021;12:7334-7349 pubmed publisher
Artigas N, Gámez B, Cubillos Rojas M, Sánchez de Diego C, Valer J, Pons G, et al. p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation. Cell Death Differ. 2017;24:2022-2031 pubmed publisher
Cino E, Soares I, Pedrote M, de Oliveira G, Silva J. Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds. Sci Rep. 2016;6:32535 pubmed publisher
Ayed A, Mulder F, Yi G, Lu Y, Kay L, Arrowsmith C. Latent and active p53 are identical in conformation. Nat Struct Biol. 2001;8:756-60 pubmed
product information
Catalog Number :
24866
Product Name :
human p53-(94-312)
article :
doi10.1038/nsb0901-756
id3363
pubmed_id11524676
bacterial resistance :
Ampicillin
cloning :
backbonepET15b
backbone_mutation
backbone_originNovagen
backbone_size5700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth notes :
E.Coli strain for epression: BL21DE3-pLysS p53 proteins are expressed better and more stable at low temperature
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5NdeI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutationContains aa 94-312.
namep53
shRNA_sequence
size218
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHis
resistance markers :
732
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA