This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
human p53-(1-393)
catalog :
24859
citations: 10
Reference
Lampart A, Krowarsch D, Biadun M, Sorensen V, Szymczyk J, Sluzalska K, et al. Intracellular FGF1 protects cells from apoptosis through direct interaction with p53. Cell Mol Life Sci. 2023;80:311 pubmed publisher
Yang D, Saeedi A, Davtyan A, Fathi M, Sherman M, Safari M, et al. Mesoscopic protein-rich clusters host the nucleation of mutant p53 amyloid fibrils. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Trujillo Uscanga A, GutiƩrrez Escolano A. Host cell p53 associates with the feline calicivirus major viral capsid protein VP1, the protease-polymerase NS6/7, and the double-stranded RNA playing a role in virus replication. Virology. 2020;550:78-88 pubmed publisher
Hurley L, Levin N, Chatterjee M, Coles J, Muszkat S, Howarth Z, et al. Evaluation of paraneoplastic antigens reveals TRIM21 autoantibodies as biomarker for early detection of ovarian cancer in combination with autoantibodies to NY-ESO-1 and TP53. Cancer Biomark. 2020;27:407-421 pubmed publisher
Cornett E, Dickson B, Krajewski K, Spellmon N, Umstead A, Vaughan R, et al. A functional proteomics platform to reveal the sequence determinants of lysine methyltransferase substrate selectivity. Sci Adv. 2018;4:eaav2623 pubmed publisher
Yang L, Li Y, Bhattacharya A, Zhang Y. PEPD is a pivotal regulator of p53 tumor suppressor. Nat Commun. 2017;8:2052 pubmed publisher
Qiao C, Lu N, Zhou Y, Ni T, Dai Y, Li Z, et al. Oroxylin A modulates mitochondrial function and apoptosis in human colon cancer cells by inducing mitochondrial translocation of wild-type p53. Oncotarget. 2016;7:17009-20 pubmed publisher
Morales D, Braun G, Pallaoro A, Chen R, Huang X, Zasadzinski J, et al. Targeted intracellular delivery of proteins with spatial and temporal control. Mol Pharm. 2015;12:600-9 pubmed publisher
Feldman D, Chen C, Punj V, Machida K. The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. PLoS ONE. 2013;8:e57312 pubmed publisher
Ayed A, Mulder F, Yi G, Lu Y, Kay L, Arrowsmith C. Latent and active p53 are identical in conformation. Nat Struct Biol. 2001;8:756-60 pubmed
product information
Catalog Number :
24859
Product Name :
human p53-(1-393)
article :
doi10.1038/nsb0901-756
id3363
pubmed_id11524676
bacterial resistance :
Ampicillin
cloning :
backbonepET15b
backbone_mutation
backbone_originNovagen
backbone_size5700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Bacterial Expression
growth notes :
E.Coli strain for epression: BL21DE3-pLysS p53 proteins are expressed better and more stable at low temperature
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5NdeI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutationFull length.
namep53
shRNA_sequence
size1179
species
9606
Homo sapiens
tags
locationN terminal on insert
tagHis
resistance markers :
732
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA