This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
3XFlag DVL2 (WT)
catalog :
24802
citations: 16
Reference
Christians A, Kesdiren E, Hennies I, Hofmann A, Trowe M, Brand F, et al. Heterozygous variants in the DVL2 interaction region of DACT1 cause CAKUT and features of Townes-Brocks syndrome 2. Hum Genet. 2023;142:73-88 pubmed publisher
Kim Y, Kim D, Zhang H, Bae C, Seong D, Kim Y, et al. DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis. BMC Biol. 2022;20:41 pubmed publisher
Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanárová O, Radaszkiewicz K, Pícková M, et al. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. elife. 2021;10: pubmed publisher
Paclíková P, Radaszkiewicz T, Potesil D, Harnoš J, Zdrahal Z, Bryja V. Roles of individual human Dishevelled paralogs in the Wnt signalling pathways. Cell Signal. 2021;85:110058 pubmed publisher
Giebel N, de Jaime Soguero A, García Del Arco A, Landry J, Tietje M, Villacorta L, et al. USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling. EMBO Rep. 2021;22:e51415 pubmed publisher
Yang Y, Jiang H, Li W, Chen L, Zhu W, Xian Y, et al. FOXM1/DVL2/Snail axis drives metastasis and chemoresistance of colorectal cancer. Aging (Albany NY). 2020;12:24424-24440 pubmed publisher
Khawaled S, Nigita G, Distefano R, Oster S, Suh S, Smith Y, et al. Pleiotropic tumor suppressor functions of WWOX antagonize metastasis. Signal Transduct Target Ther. 2020;5:43 pubmed publisher
Tang S, Chen S, Huang B, Jiang J, Wen J, Deng Y. Deoxynivalenol induces inhibition of cell proliferation via the Wnt/β-catenin signaling pathway. Biochem Pharmacol. 2019;166:12-22 pubmed publisher
Strakova K, Kowalski Jahn M, Gybel T, Valnohova J, Dhople V, Harnoš J, et al. Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization. J Biol Chem. 2018;293:18477-18493 pubmed publisher
Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, et al. The tyrosine Y2502.39 in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Cell Signal. 2017;38:85-96 pubmed publisher
Fafilek B, Hampl M, Ricankova N, Vesela I, Balek L, Kunova Bosakova M, et al. Statins do not inhibit the FGFR signaling in chondrocytes. Osteoarthritis Cartilage. 2017;25:1522-1530 pubmed publisher
Lin C, Chen H, Lin C, Wu H, Sheu J, Chen H. Apigenin-induced lysosomal degradation of ?-catenin in Wnt/?-catenin signaling. Sci Rep. 2017;7:372 pubmed publisher
Luo K, Gu X, Liu J, Zeng G, Peng L, Huang H, et al. Inhibition of disheveled-2 resensitizes cisplatin-resistant lung cancer cells through down-regulating Wnt/?-catenin signaling. Exp Cell Res. 2016;347:105-13 pubmed publisher
Kim S, Nie H, Nesin V, Tran U, Outeda P, Bai C, et al. The polycystin complex mediates Wnt/Ca(2+) signalling. Nat Cell Biol. 2016;18:752-764 pubmed publisher
Perez J, Chirieleison S, Abbott D. An IκB Kinase-Regulated Feedforward Circuit Prolongs Inflammation. Cell Rep. 2015;12:537-44 pubmed publisher
Narimatsu M, Bose R, Pye M, Zhang L, Miller B, Ching P, et al. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell. 2009;137:295-307 pubmed publisher
product information
Catalog Number :
24802
Product Name :
3XFlag DVL2 (WT)
article :
doi10.1016/j.cell.2009.02.025
id3304
pubmed_id19379695
bacterial resistance :
Ampicillin
cloning :
backbonepCMV5
backbone_mutation
backbone_origin
backbone_size4095
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5KpnI
promoter
sequencing_primer_3hGH-PA-R
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneDVL2
id1856
genbank_ids
mutation
nameDVL2
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on insert
tag3XFlag
resistance markers :
589
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA