This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pN3-Sp1FL
catalog :
24543
citations: 12
Reference
Kim S, Ban H, Lee S, Jin H. Regulation of CIRP by genetic factors of SP1 related to cold sensitivity. Front Immunol. 2022;13:994699 pubmed publisher
McDermott A, Kim K, Kasper S, Ho S, Leung Y. The androgen receptor inhibits transcription of GPER1 by preventing Sp1 and Sp3 from binding to the promoters in prostate cancer cells. Oncotarget. 2022;13:46-60 pubmed publisher
Choi H, Roh J. LH-induced Transcriptional Regulation of Klf4 Expression in Granulosa Cells Occurs via the cAMP/PKA Pathway and Requires a Putative Sp1 Binding Site. Int J Mol Sci. 2020;21: pubmed publisher
Zhang C, Wang N, Tan H, Guo W, Chen F, Zhong Z, et al. Direct inhibition of the TLR4/MyD88 pathway by geniposide suppresses HIF-1α-independent VEGF expression and angiogenesis in hepatocellular carcinoma. Br J Pharmacol. 2020;177:3240-3257 pubmed publisher
Long J, Liao G, Wang Y, Tang D. Specific protein 1, c-Abl and ERK1/2 form a regulatory loop. J Cell Sci. 2019;132: pubmed publisher
Fletcher S, Grou C, Legrand A, Chen X, Soderstrom K, Poletto M, et al. Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent DNA damage. Nucleic Acids Res. 2018;46:1834-1846 pubmed publisher
Li J, Gao H, Meng L, Yin L. Mithramycin inhibits epithelial-to-mesenchymal transition and invasion by downregulating SP1 and SNAI1 in salivary adenoid cystic carcinoma. Tumour Biol. 2017;39:1010428317708697 pubmed publisher
Wang X, Li C, Liang A, Peng Y, Sun J, Huang D, et al. Regulation of a disintegrins and metalloproteinase with thrombospondin motifs 7 during inflammation in nucleus pulposus (NP) cells: role of AP-1, Sp1 and NF-?B signaling. Inflamm Res. 2016;65:951-962 pubmed
Thakur B, Dasgupta N, Ta A, Das S. Physiological TLR5 expression in the intestine is regulated by differential DNA binding of Sp1/Sp3 through simultaneous Sp1 dephosphorylation and Sp3 phosphorylation by two different PKC isoforms. Nucleic Acids Res. 2016;44:5658-72 pubmed publisher
Ye W, Zhou J, Markova D, Tian Y, Li J, Anderson D, et al. Xylosyltransferase-1 expression is refractory to inhibition by the inflammatory cytokines tumor necrosis factor α and IL-1β in nucleus pulposus cells: novel regulation by AP-1, Sp1, and Sp3. Am J Pathol. 2015;185:485-95 pubmed publisher
Lafleur V, Richard S, Richard D. Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1. Mol Biol Cell. 2014;25:925-35 pubmed publisher
Chang Y, Chen K, Chen C, Lin M, Sun Y, Lee J, et al. SH2B1? interacts with STAT3 and enhances fibroblast growth factor 1-induced gene expression during neuronal differentiation. Mol Cell Biol. 2014;34:1003-19 pubmed publisher
product information
Catalog Number :
24543
Product Name :
pN3-Sp1FL
article :
doi
id3277
pubmed_id
bacterial resistance :
Kanamycin
cloning :
backbonepN3
backbone_mutation
backbone_originGuntram Suske, Addgene plasmid 24544
backbone_size4000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
pN3-Control vector also available from Addgene 2 nucleotide mismatches with author sequence detected in the most 3 -UTR. They do not affect the coding sequence of Sp1.
origin :
37
pi :
alt_names
transcription factor Sp1
cloning
clone_methodRestriction Enzyme
cloning_site_3XhoI
cloning_site_5XhoI
promoter
sequencing_primer_3SV40pA-R
sequencing_primer_5AATCAACGGGACTTTCC, CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliases
geneSP1
id6667
genbank_ids
mutation
nameSp1FL
shRNA_sequence
size4200
species
9606
Homo sapiens
tags
resistance markers :
710
tags :
Unknown
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA