This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMVHA EED wt
catalog :
24231
citations: 7
Reference
Xiang C, Frietze K, Bi Y, Li Y, Dal Pozzo V, Pal S, et al. RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021;41:e0052620 pubmed publisher
Perrigue P, Rakoczy M, Pawlicka K, Belter A, Giel Pietraszuk M, Naskret Barciszewska M, et al. Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Cancers (Basel). 2020;12: pubmed publisher
Potjewyd F, Turner A, Beri J, Rectenwald J, Norris Drouin J, Cholensky S, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2019;: pubmed publisher
Burr M, Sparbier C, Chan K, Chan Y, Kersbergen A, Lam E, et al. An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer. Cancer Cell. 2019;36:385-401.e8 pubmed publisher
Papoutsoglou P, Tsubakihara Y, Caja L, Morén A, Pallis P, Ameur A, et al. The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity. Cell Rep. 2019;28:3182-3198.e11 pubmed publisher
Wang A, Juan A, Ko K, Tsai P, Zare H, Dell Orso S, et al. The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins. Mol Cell. 2017;68:398-413.e6 pubmed publisher
Bracken A, Pasini D, Capra M, Prosperini E, Colli E, Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 2003;22:5323-35 pubmed
product information
Catalog Number :
24231
Product Name :
pCMVHA EED wt
article :
doi10.1093/emboj/cdg542
id3215
pubmed_id14532106
bacterial resistance :
Ampicillin
cloning :
backbonepCMVHA
backbone_mutation
backbone_origin
backbone_size6600
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth strain :
Mammalian expression of human EED with HA tag
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5BamHI
promoterCMV
sequencing_primer_3Bglob-pA-R 5'-ttttggcagagggaaaaaga-3'
sequencing_primer_5Bglob-intron-F (5'-ctggtcatcatcctgccttt-3')
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCOGIS, HEED, WAIT1
geneEED
id8726
genbank_ids
mutation
nameEED
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
resistance markers :
705
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA