Yeh D, Liu C, Hernández J, Tahara S, Tsukamoto H, Machida K. Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal. iScience. 2023;26:107035 pubmed publisher

Xiang C, Frietze K, Bi Y, Li Y, Dal Pozzo V, Pal S, et al. RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021;41:e0052620 pubmed publisher

Allas L, Brochard S, Rochoux Q, Ribet J, Dujarrier C, Veyssiere A, et al. EZH2 inhibition reduces cartilage loss and functional impairment related to osteoarthritis. Sci Rep. 2020;10:19577 pubmed publisher

Du L, Fakih M, Rosen S, Chen Y. SUMOylation of E2F1 Regulates Expression of EZH2. Cancer Res. 2020;80:4212-4223 pubmed publisher

Muller A, Dickmanns A, Resch C, Schakel K, Hailfinger S, Dobbelstein M, et al. The CDK4/6-EZH2 pathway is a potential therapeutic target for psoriasis. J Clin Invest. 2020;: pubmed publisher

Singh A, Verma A, Singh A, Arya R, Maheshwari S, Chaturvedi P, et al. Salinomycin inhibits epigenetic modulator EZH2 to enhance death receptors in colon cancer stem cells. Epigenetics. 2020;:1-18 pubmed publisher

Perrigue P, Rakoczy M, Pawlicka K, Belter A, Giel Pietraszuk M, Naskret Barciszewska M, et al. Cancer Stem Cell-Inducing Media Activates Senescence Reprogramming in Fibroblasts. Cancers (Basel). 2020;12: pubmed publisher

Wohlberedt K, Klusmann I, Derevyanko P, Henningsen K, Choo J, Manzini V, et al. Mdm4 supports DNA replication in a p53-independent fashion. Oncogene. 2020;39:4828-4843 pubmed publisher

Subuddhi A, Kumar M, Majumder D, Sarkar A, Ghosh Z, Vasudevan M, et al. Unraveling the role of H3K4 trimethylation and lncRNA HOTAIR in SATB1 and DUSP4-dependent survival of virulent Mycobacterium tuberculosis in macrophages. Tuberculosis (Edinb). 2020;120:101897 pubmed publisher

Imai Sumida M, Dasgupta P, Kulkarni P, Shiina M, Hashimoto Y, Shahryari V, et al. Genistein Represses HOTAIR/Chromatin Remodeling Pathways to Suppress Kidney Cancer. Cell Physiol Biochem. 2020;54:53-70 pubmed publisher

Potjewyd F, Turner A, Beri J, Rectenwald J, Norris Drouin J, Cholensky S, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2019;: pubmed publisher

Xie Q, Zhu Z, He Y, Zhang Z, Zhang Y, Wang Y, et al. A lactate-induced Snail/STAT3 pathway drives GPR81 expression in lung cancer cells. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165576 pubmed publisher

Papoutsoglou P, Tsubakihara Y, Caja L, Morén A, Pallis P, Ameur A, et al. The TGFB2-AS1 lncRNA Regulates TGF-β Signaling by Modulating Corepressor Activity. Cell Rep. 2019;28:3182-3198.e11 pubmed publisher

Andrews D, Oliviero G, De Chiara L, Watson A, Rochford E, Wynne K, et al. Unravelling the transcriptional responses of TGF-β: Smad3 and EZH2 constitute a regulatory switch that controls neuroretinal epithelial cell fate specification. FASEB J. 2019;33:6667-6681 pubmed publisher

Li F, Zeng Z, Xing S, Gullicksrud J, Shan Q, Choi J, et al. Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf. Nat Commun. 2018;9:5452 pubmed publisher

El Ayachi I, Fatima I, Wend P, Alva Ornelas J, Runke S, Kuenzinger W, et al. The WNT10B Network Is Associated with Survival and Metastases in Chemoresistant Triple-Negative Breast Cancer. Cancer Res. 2019;79:982-993 pubmed publisher

Kumari K, Adhya A, Rath A, Reddy P, Mishra S. Estrogen-related receptors alpha, beta and gamma expression and function is associated with transcriptional repressor EZH2 in breast carcinoma. BMC Cancer. 2018;18:690 pubmed publisher

Caruso L, Martin K, Lauretti E, Hulse M, Siciliano M, Lupey Green L, et al. Poly(ADP-ribose) Polymerase 1, PARP1, modifies EZH2 and inhibits EZH2 histone methyltransferase activity after DNA damage. Oncotarget. 2018;9:10585-10605 pubmed publisher

Billingsley K, Manca M, Gianfrancesco O, Collier D, Sharp H, Bubb V, et al. Regulatory characterisation of the schizophrenia-associated CACNA1C proximal promoter and the potential role for the transcription factor EZH2 in schizophrenia aetiology. Schizophr Res. 2018;199:168-175 pubmed publisher

Wan L, Xu K, Wei Y, Zhang J, Han T, Fry C, et al. Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function. Mol Cell. 2018;69:279-291.e5 pubmed publisher

Wang A, Juan A, Ko K, Tsai P, Zare H, Dell Orso S, et al. The Elongation Factor Spt6 Maintains ESC Pluripotency by Controlling Super-Enhancers and Counteracting Polycomb Proteins. Mol Cell. 2017;68:398-413.e6 pubmed publisher

Lu W, Liu S, Li B, Xie Y, Izban M, Ballard B, et al. SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer. Oncogene. 2017;36:1364-1373 pubmed publisher

Lawrence C, Baldwin A. Non-Canonical EZH2 Transcriptionally Activates RelB in Triple Negative Breast Cancer. PLoS ONE. 2016;11:e0165005 pubmed publisher

Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, et al. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. 2016;7:56338-56354 pubmed publisher

Sengupta D, Byrum S, Avaritt N, Davis L, Shields B, Mahmoud F, et al. Quantitative Histone Mass Spectrometry Identifies Elevated Histone H3 Lysine 27 (Lys27) Trimethylation in Melanoma. Mol Cell Proteomics. 2016;15:765-75 pubmed publisher

Koo J, Mazei Robison M, LaPlant Q, Egervári G, Braunscheidel K, Adank D, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci. 2015;18:415-22 pubmed publisher

Iannetti A, Ledoux A, Tudhope S, Sellier H, Zhao B, Mowla S, et al. Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence. PLoS Genet. 2014;10:e1004642 pubmed publisher

Bracken A, Pasini D, Capra M, Prosperini E, Colli E, Helin K. EZH2 is downstream of the pRB-E2F pathway, essential for proliferation and amplified in cancer. EMBO J. 2003;22:5323-35 pubmed