This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
EGFPC1-huNFATc1EE-WT
catalog :
24219
citations: 12
Reference
Tanwar J, Ahuja K, Sharma A, Sehgal P, Ranjan G, Sultan F, et al. Mitochondrial calcium signaling mediated transcriptional regulation of keratin filaments is a critical determinant of melanogenesis. bioRxiv. 2023;: pubmed publisher
Suthon S, Lin J, Perkins R, Crockarell J, Miranda Carboni G, Krum S. Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts. Am J Hum Genet. 2022;109:97-115 pubmed publisher
Ajayi Smith A, van der Watt P, Mkwanazi N, Carden S, Trent J, Leaner V. Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells. Exp Cell Res. 2021;404:112637 pubmed publisher
Im J, Kim B, Yoon S, Cho B, Baek Y, Kang M, et al. DGG-100629 inhibits lung cancer growth by suppressing the NFATc1/DDIAS/STAT3 pathway. Exp Mol Med. 2021;53:643-653 pubmed publisher
Zhao X, Nedvetsky P, Stanchi F, Vion A, Popp O, Zühlke K, et al. Endothelial PKA activity regulates angiogenesis by limiting autophagy through phosphorylation of ATG16L1. elife. 2019;8: pubmed publisher
Carden S, van der Watt P, Chi A, Ajayi Smith A, Hadley K, Leaner V. A tight balance of Karyopherin β1 expression is required in cervical cancer cells. BMC Cancer. 2018;18:1123 pubmed publisher
Kycia I, Wolford B, Huyghe J, Fuchsberger C, Vadlamudi S, Kursawe R, et al. A Common Type 2 Diabetes Risk Variant Potentiates Activity of an Evolutionarily Conserved Islet Stretch Enhancer and Increases C2CD4A and C2CD4B Expression. Am J Hum Genet. 2018;102:620-635 pubmed publisher
Perroud J, Bernheim L, Frieden M, Koenig S. Distinct roles of NFATc1 and NFATc4 in human primary myoblast differentiation and in the maintenance of reserve cells. J Cell Sci. 2017;130:3083-3093 pubmed publisher
van der Watt P, Chi A, Stelma T, Stowell C, Strydom E, Carden S, et al. Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic. Mol Cancer Ther. 2016;15:560-73 pubmed publisher
Shiny A, Regin B, Mohan V, Balasubramanyam M. Coordinated augmentation of NFAT and NOD signaling mediates proliferative VSMC phenotype switch under hyperinsulinemia. Atherosclerosis. 2016;246:257-66 pubmed publisher
Yost E, Hynes T, Hartle C, Ott B, Berlot C. Inhibition of G-protein βγ signaling enhances T cell receptor-stimulated interleukin 2 transcription in CD4+ T helper cells. PLoS ONE. 2015;10:e0116575 pubmed publisher
Beals C, Clipstone N, Ho S, Crabtree G. Nuclear localization of NF-ATc by a calcineurin-dependent, cyclosporin-sensitive intramolecular interaction. Genes Dev. 1997;11:824-34 pubmed
product information
Catalog Number :
24219
Product Name :
EGFPC1-huNFATc1EE-WT
article :
doi10.1101/gad.11.7.824
id3205
pubmed_id9106655
bacterial resistance :
Kanamycin
cloning :
backbonepEGFPC1
backbone_mutation
backbone_originClonetech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
NFAT2
cloning
clone_methodRestriction Enzyme
cloning_site_3BamH1
cloning_site_5Bgl II
promoter
sequencing_primer_3
sequencing_primer_5EGFP C seq. primer (#6478-1)
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesNF-ATC, NF-ATc1.2, NFAT2, NFATc
geneNFATC1
id4772
genbank_ids
mutation
nameNFATc1
shRNA_sequence
size2147
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
locationC terminal on insert
tagEE
resistance markers :
97
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA