This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HIR Y1162F
catalog :
24052
citations: 1
Reference
Jacob K, Whittaker J, Stanley F. Insulin receptor tyrosine kinase activity and phosphorylation of tyrosines 1162 and 1163 are required for insulin-increased prolactin gene expression. Mol Cell Endocrinol. 2002;186:7-16 pubmed
product information
Catalog Number :
24052
Product Name :
HIR Y1162F
article :
doi10.1016/S0303-7207(01)00674-8
id3155
pubmed_id11850117
bacterial resistance :
Ampicillin
cloning :
backbonepRT3
backbone_mutation
backbone_origin
backbone_size3000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
The amino acid assignments for the mutations come from an alternate intron that shifts the location of these sites so the K1030R corresponds to other mutations made by others that are K1018R. The clone of the receptor came from William Rutter (Cell 45, 721-732, 1986) who has the same numbering as the Stanley lab. Other researchers do not have the 12 aa alternate intron, and the relevancy of this intron is not fully understood.
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5SalI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD220, HHF5
geneINSR
id3643
genbank_ids
mutationY1162F
nameInsulin Receptor
shRNA_sequence
size4600
species
9606
Homo sapiens
tags
resistance markers :
678
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA