This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
HIR WT
catalog :
24049
citations: 7
Reference
Liu S, Li X, Yang J, Zhu R, Fan Z, Xu X, et al. Misfolded proinsulin impairs processing of precursor of insulin receptor and insulin signaling in β cells. FASEB J. 2019;33:11338-11348 pubmed publisher
Wu D, Lv D, Zhang T, Guo L, Ma F, Zhang C, et al. Antitumor effects of β-elemene via targeting the phosphorylation of insulin receptor. Endocr Relat Cancer. 2018;: pubmed publisher
Chen L, Chai K. Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases. Oncotarget. 2017;8:56490-56505 pubmed publisher
Swaminathan S, Ahlschwede K, Sarma V, Curran G, Omtri R, Decklever T, et al. Insulin differentially affects the distribution kinetics of amyloid beta 40 and 42 in plasma and brain. J Cereb Blood Flow Metab. 2018;38:904-918 pubmed publisher
Lv D, Liu J, Guo L, Wu D, Matsumoto K, Huang L. PRAS40 deregulates apoptosis in Ewing sarcoma family tumors by enhancing the insulin receptor/Akt and mTOR signaling pathways. Am J Cancer Res. 2016;6:486-97 pubmed
Qian X, Kraft J, Ni Y, Zhao F. Production of recombinant human proinsulin in the milk of transgenic mice. Sci Rep. 2014;4:6465 pubmed publisher
Jacob K, Whittaker J, Stanley F. Insulin receptor tyrosine kinase activity and phosphorylation of tyrosines 1162 and 1163 are required for insulin-increased prolactin gene expression. Mol Cell Endocrinol. 2002;186:7-16 pubmed
product information
Catalog Number :
24049
Product Name :
HIR WT
article :
doi10.1016/S0303-7207(01)00674-8
id3155
pubmed_id11850117
bacterial resistance :
Ampicillin
cloning :
backbonepRT3
backbone_mutation
backbone_origin
backbone_size3000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5SalI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCD220, HHF5
geneINSR
id3643
genbank_ids
mutation
nameInsulin Receptor
shRNA_sequence
size4600
species
9606
Homo sapiens
tags
resistance markers :
678
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA