This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCI-SEP_NR2A
catalog :
23997
citations: 7
Reference
Woo D, Hur Y, Jang M, Justin Lee C, Park M. Inhibitors of synaptic vesicle exocytosis reduce surface expression of postsynaptic glutamate receptors. Anim Cells Syst (Seoul). 2020;24:341-348 pubmed publisher
Rosendo Pineda M, Vicente J, Vivas O, Pacheco J, Loza Huerta A, Sampieri A, et al. Phosphorylation of NMDA receptors by cyclin B/CDK1 modulates calcium dynamics and mitosis. Commun Biol. 2020;3:665 pubmed publisher
Zhu M, Cortese G, Waites C. Parkinson's disease-linked Parkin mutations impair glutamatergic signaling in hippocampal neurons. BMC Biol. 2018;16:100 pubmed publisher
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
Wang N, Chen L, Cheng N, Zhang J, Tian T, Lu W. Active calcium/calmodulin-dependent protein kinase II (CaMKII) regulates NMDA receptor mediated postischemic long-term potentiation (i-LTP) by promoting the interaction between CaMKII and NMDA receptors in ischemia. Neural Plast. 2014;2014:827161 pubmed publisher
Swanger S, He Y, Richter J, Bassell G. Dendritic GluN2A synthesis mediates activity-induced NMDA receptor insertion. J Neurosci. 2013;33:8898-908 pubmed publisher
Kopec C, Li B, Wei W, Boehm J, Malinow R. Glutamate receptor exocytosis and spine enlargement during chemically induced long-term potentiation. J Neurosci. 2006;26:2000-9 pubmed
product information
Catalog Number :
23997
Product Name :
pCI-SEP_NR2A
article :
doi10.1523/JNEUROSCI.3918-05.2006
id3145
pubmed_id16481433
bacterial resistance :
Ampicillin
cloning :
backbonepCI
backbone_mutation
backbone_origin
backbone_size4000
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
See attached map for additional plasmid features. The super-ecliptic pHluorin (SEP) coding sequence was inserted three amino acids downstream of the predicted signal peptide cleavage site.
growth temp :
JM109 Cells
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3NotI
cloning_site_5XhoI
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesGluN2A, NMDAR2A, NR2A
geneGrin2a
id24409
genbank_ids
mutation
nameNR2A
shRNA_sequence
size5800
species
10116
Rattus norvegicus
tags
locationN terminal on insert
tagSEP
resistance markers :
671
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA