This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
p5953 pcDNA-Xpress-His-USP15
catalog :
23216
citations: 6
Reference
Messa L, Celegato M, Bertagnin C, Mercorelli B, Alvisi G, Banks L, et al. The Dimeric Form of HPV16 E6 Is Crucial to Drive YAP/TAZ Upregulation through the Targeting of hScrib. Cancers (Basel). 2021;13: pubmed publisher
Niederkorn M, Hueneman K, Choi K, Varney M, Romano L, Pujato M, et al. TIFAB Regulates USP15-Mediated p53 Signaling during Stressed and Malignant Hematopoiesis. Cell Rep. 2020;30:2776-2790.e6 pubmed publisher
Teyra J, Singer A, Schmitges F, Jaynes P, Kit Leng Lui S, Polyak M, et al. Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 2019;27:590-605.e5 pubmed publisher
Zou Q, Jin J, Hu H, Li H, Romano S, Xiao Y, et al. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nat Immunol. 2014;15:562-70 pubmed publisher
Azoitei N, Hoffmann C, Ellegast J, Ball C, Obermayer K, Gößele U, et al. Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33. J Exp Med. 2012;209:697-711 pubmed publisher
Vos R, Altreuter J, White E, Howley P. The ubiquitin-specific peptidase USP15 regulates human papillomavirus type 16 E6 protein stability. J Virol. 2009;83:8885-92 pubmed publisher
product information
Catalog Number :
23216
Product Name :
p5953 pcDNA-Xpress-His-USP15
article :
doi10.1128/JVI.00605-09
id3105
pubmed_id19553310
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA-4C
backbone_mutation
backbone_originInvitrogen
backbone_size5300
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5NotI
promoter
sequencing_primer_3BGH-rev
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesUNPH-2, UNPH4
geneUSP15
id9958
genbank_ids
mutation
nameUSP15
shRNA_sequence
size2900
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHis
locationN terminal on backbone
tagXpress
resistance markers :
209
tags :
Unknown
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA