This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti6/V5-p53_R273H
catalog :
22934
citations: 11
Reference
Cui B, Song L, Wang Q, Li K, He Q, Wu X, et al. Non-small cell lung cancers (NSCLCs) oncolysis using coxsackievirus B5 and synergistic DNA-damage response inhibitors. Signal Transduct Target Ther. 2023;8:366 pubmed publisher
Liu Y, Azizian N, Sullivan D, Li Y. mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters. Nat Commun. 2022;13:7047 pubmed publisher
Mej xed a Hern xe1 ndez J, Raghu D, Caramia F, Clemons N, Fujihara K, Riseborough T, et al. Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status. Cancers (Basel). 2022;14: pubmed publisher
McCann J, Vasilevskaya I, McNair C, Gallagher P, Neupane N, de Leeuw R, et al. Mutant p53 elicits context-dependent pro-tumorigenic phenotypes. Oncogene. 2021;: pubmed publisher
Jung S, Kim D, Choi Y, Kim S, Park H, Lee H, et al. Contribution of p53 in sensitivity to EGFR tyrosine kinase inhibitors in non-small cell lung cancer. Sci Rep. 2021;11:19667 pubmed publisher
Ma S, McGuire M, Mangala L, Lee S, Stur E, Hu W, et al. Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype. Cell Rep. 2021;34:108726 pubmed publisher
Segura Collar B, Gargini R, Tovar Ambel E, Hernández SanMiguel E, Epifano C, Perez de Castro I, et al. The EGFR-TMEM167A-p53 Axis Defines the Aggressiveness of Gliomas. Cancers (Basel). 2020;12: pubmed publisher
Sa J, Hwang J, Cho Y, Ryu J, Choi J, Jeong S, et al. Pharmacogenomic analysis of patient-derived tumor cells in gynecologic cancers. Genome Biol. 2019;20:253 pubmed publisher
Goswami M, Vandenberg K, Han S, Wang L, Singh B, Weiss T, et al. Identification of TP53RK Binding Protein (TPRKB) dependency in TP53-deficient cancers. Mol Cancer Res. 2019;: pubmed publisher
Artigas N, Gámez B, Cubillos Rojas M, Sánchez de Diego C, Valer J, Pons G, et al. p53 inhibits SP7/Osterix activity in the transcriptional program of osteoblast differentiation. Cell Death Differ. 2017;24:2022-2031 pubmed publisher
Junk D, Vrba L, Watts G, Oshiro M, Martinez J, Futscher B. Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia. 2008;10:450-61 pubmed
product information
Catalog Number :
22934
Product Name :
pLenti6/V5-p53_R273H
article :
doi
id3042
pubmed_id18472962
bacterial resistance :
Ampicillin
cloning :
backbonepLenti6/V5-D-Topo
backbone_mutation
backbone_origin
backbone_size6963
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth temp :
Stbl3 (Invitrogen)
origin :
37
pi :
alt_names
TP53
cloning
clone_methodTOPO Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5CMV
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutationR273H Mutant
nametumor protein 53
shRNA_sequence
size1179
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagV5
resistance markers :
658
tags :
Unknown
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA