This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pLenti6/V5-p53_R280K
catalog :
22933
citations: 4
Reference
Goswami M, Vandenberg K, Han S, Wang L, Singh B, Weiss T, et al. Identification of TP53RK Binding Protein (TPRKB) dependency in TP53-deficient cancers. Mol Cancer Res. 2019;: pubmed publisher
Hashimoto A, Hashimoto S, Sugino H, Yoshikawa A, Onodera Y, Handa H, et al. ZEB1 induces EPB41L5 in the cancer mesenchymal program that drives ARF6-based invasion, metastasis and drug resistance. Oncogenesis. 2016;5:e259 pubmed publisher
Hashimoto A, Oikawa T, Hashimoto S, Sugino H, Yoshikawa A, Otsuka Y, et al. P53- and mevalonate pathway-driven malignancies require Arf6 for metastasis and drug resistance. J Cell Biol. 2016;213:81-95 pubmed publisher
Junk D, Vrba L, Watts G, Oshiro M, Martinez J, Futscher B. Different mutant/wild-type p53 combinations cause a spectrum of increased invasive potential in nonmalignant immortalized human mammary epithelial cells. Neoplasia. 2008;10:450-61 pubmed
product information
Catalog Number :
22933
Product Name :
pLenti6/V5-p53_R280K
article :
doi
id3042
pubmed_id18472962
bacterial resistance :
Ampicillin
cloning :
backbonepLenti6/V5-D-Topo
backbone_mutation
backbone_origin
backbone_size6963
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Lentiviral
growth temp :
Stbl3 (Invitrogen)
origin :
37
pi :
alt_names
TP53
cloning
clone_methodTOPO Cloning
cloning_site_3
cloning_site_5
promoter
sequencing_primer_3
sequencing_primer_5CMV
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesBCC7, BMFS5, LFS1, P53, TRP53
geneTP53
id7157
genbank_ids
mutationR280K mutant
nametumor protein 53
shRNA_sequence
size1179
species
9606
Homo sapiens
tags
locationC terminal on backbone
tagv5
resistance markers :
658
tags :
Unknown
terms :
Blasticidin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA