This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pcDNA4-Chk1-Flag
catalog :
22894
citations: 6
Reference
Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings J, et al. ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization. Cell Rep. 2022;38:110216 pubmed publisher
Moses N, Zhang M, Wu J, Hu C, Xiang S, Geng X, et al. HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells. 2020;9: pubmed publisher
Kramer D, Stark N, Schulz Heddergott R, Erytch N, Edmunds S, Roßmann L, et al. Strong antitumor synergy between DNA crosslinking and HSP90 inhibition causes massive premitotic DNA fragmentation in ovarian cancer cells. Cell Death Differ. 2017;24:300-316 pubmed publisher
Best A, James K, Dalgliesh C, Hong E, Kheirolahi Kouhestani M, Curk T, et al. Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons. Nat Commun. 2014;5:4760 pubmed publisher
Mohni K, Dee A, Smith S, Schumacher A, Weller S. Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins. J Virol. 2013;87:531-42 pubmed publisher
Unsal Kaçmaz K, Chastain P, Qu P, Minoo P, Cordeiro Stone M, Sancar A, et al. The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement. Mol Cell Biol. 2007;27:3131-42 pubmed
product information
Catalog Number :
22894
Product Name :
pcDNA4-Chk1-Flag
article :
doi10.1128/MCB.02190-06
id3035
pubmed_id17296725
bacterial resistance :
Ampicillin
cloning :
backbonepcDNA4a
backbone_mutation
backbone_originInvitrogen
backbone_size5100
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
CHEK1
cloning
clone_methodRestriction Enzyme
cloning_site_3PmeI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCHK1, OZEMA21
geneCHEK1
id1111
genbank_ids
AK300082.1
mutation
nameChk1
shRNA_sequence
size1430
species
9606
Homo sapiens
tags
locationC terminal on insert
tagFlag
plasmid copy :
Stephen Elledge; pBSChk1
resistance markers :
436
tags :
High Copy
terms :
Zeocin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA