This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
Flag-HA-USP8
catalog :
22608
citations: 6
Reference
O Dea R, Kazi N, Hoffmann Benito A, Zhao Z, Recknagel S, Wendrich K, et al. Molecular basis for ubiquitin/Fubi cross-reactivity in USP16 and USP36. Nat Chem Biol. 2023;: pubmed publisher
Kim M, Choi B, Kim J, Min Y, Kwon D, Son J, et al. USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4. Transl Oncol. 2022;15:101250 pubmed publisher
Chen M, Amado N, Tan J, Reis A, Ge M, Abreu J, et al. TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis. elife. 2020;9: pubmed publisher
Alexopoulou Z, Lang J, Perrett R, Elschami M, Hurry M, Kim H, et al. Deubiquitinase Usp8 regulates ?-synuclein clearance and modifies its toxicity in Lewy body disease. Proc Natl Acad Sci U S A. 2016;113:E4688-97 pubmed publisher
Durcan T, Tang M, Pérusse J, Dashti E, Aguileta M, McLelland G, et al. USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin. EMBO J. 2014;33:2473-91 pubmed publisher
Sowa M, Bennett E, Gygi S, Harper J. Defining the human deubiquitinating enzyme interaction landscape. Cell. 2009;138:389-403 pubmed publisher
product information
Catalog Number :
22608
Product Name :
Flag-HA-USP8
article :
doi10.1016/j.cell.2009.04.042
id2846
pubmed_id19615732
bacterial resistance :
Ampicillin
cloning :
backbonepDEST_Tet_ON_CMV_N_FLAG_HA_PGK_puro
backbone_mutation
backbone_originHarper_Lab
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Retroviral
origin :
37
pi :
alt_names
ubiquitin specific peptidase 8
FLJ34456, HumORF8, KIAA0055, MGC129718, UBPY
cloning
clone_methodGateway Cloning
cloning_site_3GATEWAY_LR
cloning_site_5GATEWAY_LR
promoter
sequencing_primer_3
sequencing_primer_5CMV_forward
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesHumORF8, PITA4, SPG59, UBPY
geneUSP8
id9101
genbank_ids
BC110590
mutationNone
nameUSP8
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagHA
locationN terminal on backbone
tagFLAG
plasmid copy :
MGC/Open
resistance markers :
191
tags :
High Copy
terms :
Puromycin
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA