This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFPC1-human APPL1
catalog :
22198
citations: 5
Reference
York H, Joshi K, Wright C, Kreplin L, Rodgers S, Moorthi U, et al. Deterministic early endosomal maturations emerge from a stochastic trigger-and-convert mechanism. Nat Commun. 2023;14:4652 pubmed publisher
York H, Patil A, Moorthi U, Kaur A, Bhowmik A, Hyde G, et al. Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors. Commun Biol. 2021;4:224 pubmed publisher
Chen P, Luo R, Jian X, Randazzo P. The Arf6 GTPase-activating proteins ARAP2 and ACAP1 define distinct endosomal compartments that regulate integrin α5β1 traffic. J Biol Chem. 2014;289:30237-48 pubmed publisher
Friedman J, DiBenedetto J, West M, Rowland A, Voeltz G. Endoplasmic reticulum-endosome contact increases as endosomes traffic and mature. Mol Biol Cell. 2013;24:1030-40 pubmed publisher
Erdmann K, Mao Y, McCrea H, Zoncu R, Lee S, Paradise S, et al. A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev Cell. 2007;13:377-90 pubmed
product information
Catalog Number :
22198
Product Name :
pEGFPC1-human APPL1
article :
doi10.1016/j.devcel.2007.08.004
id2883
pubmed_id17765681
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1
backbone_mutation
backbone_originClontech
backbone_size
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Bacterial Expression
origin :
37
pi :
alt_names
APPL1
DIP13alpha
cloning
clone_methodRestriction Enzyme
cloning_site_3EcoRI
cloning_site_5XhoI
promoter
sequencing_primer_3EGFP-C Sequencing Primer
sequencing_primer_5EGFP-N Sequencing Primere
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAPPL, DIP13alpha, MODY14
geneAPPL1
id26060
genbank_ids
NM_012096
mutation
nameAdaptor protein containing PH domain, PTB domain and Leucine zipper motif
shRNA_sequence
size
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
resistance markers :
625
tags :
High Copy
terms :
Neomycin (select with G418)
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA