This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pEGFP-C1-A20
catalog :
22141
citations: 8
Reference
Sheveleva O, Protasova E, Nenasheva T, Butorina N, Melnikova V, Gerasimova T, et al. A Model of iPSC-Derived Macrophages with TNFAIP3 Overexpression Reveals the Peculiarities of TNFAIP3 Protein Expression and Function in Human Macrophages. Int J Mol Sci. 2023;24: pubmed publisher
El Khouri E, Diab F, Louvrier C, Assrawi E, Daskalopoulou A, Nguyen A, et al. A critical region of A20 unveiled by missense TNFAIP3 variations that lead to autoinflammation. elife. 2023;12: pubmed publisher
Kunzmann S, Hütten M, Ottensmeier B, Kramer B, Fehrholz M. A20 Is Increased in Fetal Lung in a Sheep LPS Model of Chorioamnionitis. Oxid Med Cell Longev. 2022;2022:6421419 pubmed publisher
Iorga A, Donovan K, Shojaie L, Johnson H, Kwok J, Suda J, et al. Interaction of RIPK1 and A20 modulates MAPK signaling in murine acetaminophen toxicity. J Biol Chem. 2021;:100300 pubmed publisher
Yao D, Xu L, Xu O, Li R, Chen M, Shen H, et al. O-Linked ?-N-Acetylglucosamine Modification of A20 Enhances the Inhibition of NF-?B (Nuclear Factor-?B) Activation and Elicits Vascular Protection After Acute Endoluminal Arterial Injury. Arterioscler Thromb Vasc Biol. 2018;38:1309-1320 pubmed publisher
Zhou Q, Wang H, Schwartz D, Stoffels M, Park Y, Zhang Y, et al. Loss-of-function mutations in TNFAIP3 leading to A20 haploinsufficiency cause an early-onset autoinflammatory disease. Nat Genet. 2016;48:67-73 pubmed publisher
Ahmed N, Zeng M, Sinha I, Polin L, Wei W, Rathinam C, et al. The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation. Nat Immunol. 2011;12:1176-83 pubmed publisher
Li L, Hailey D, Soetandyo N, Li W, Lippincott Schwartz J, Shu H, et al. Localization of A20 to a lysosome-associated compartment and its role in NFkappaB signaling. Biochim Biophys Acta. 2008;1783:1140-9 pubmed publisher
product information
Catalog Number :
22141
Product Name :
pEGFP-C1-A20
article :
doi10.1016/j.bbamcr.2008.01.029
id2865
pubmed_id18329387
bacterial resistance :
Kanamycin
cloning :
backbonepEGFP-C1
backbone_mutation
backbone_originclontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
cloning
clone_methodRestriction Enzyme
cloning_site_3SalI
cloning_site_5BglII
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesA20, AIFBL1, AISBL, OTUD7C, TNFA1P2
geneTNFAIP3
id7128
genbank_ids
mutation
nameA20
shRNA_sequence
size2373
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagGFP
plasmid copy :
Dr. Hong-bing Shu Wuhan University China
resistance markers :
835
tags :
Low Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA