This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pCMV4-3 HA/IkB-alpha
catalog :
21985
citations: 8
Reference
Lim Y, Lin H, Chu T, Lim Y. WBP2 promotes BTRC mRNA stability to drive migration and invasion in triple-negative breast cancer via NF-κB activation. Mol Oncol. 2021;: pubmed publisher
Miyauchi T, Suzuki S, Takeda M, Peh J, Aiba M, Natsuga K, et al. Altered replication stress response due to CARD14 mutations promotes recombination-induced revertant mosaicism. Am J Hum Genet. 2021;108:1026-1039 pubmed publisher
Kudriaeva A, Livneh I, Baranov M, Ziganshin R, Tupikin A, Zaitseva S, et al. In-depth characterization of ubiquitin turnover in mammalian cells by fluorescence tracking. Cell Chem Biol. 2021;28:1192-1205.e9 pubmed publisher
Asare Y, Campbell James T, Bokov Y, Yu L, Prestel M, El Bounkari O, et al. Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability. Circ Res. 2020;127:811-823 pubmed publisher
Qadir A, Stults A, Murmann A, Peter M. The mechanism of how CD95/Fas activates the Type I IFN/STAT1 axis, driving cancer stemness in breast cancer. Sci Rep. 2020;10:1310 pubmed publisher
Wu D, Lau A, Yu F, Cai N, Dai L, Ok Kim M, et al. Extracellular signal-regulated kinase 8-mediated NF-κB activation increases sensitivity of human lung cancer cells to arsenic trioxide. Oncotarget. 2017;8:49144-49155 pubmed publisher
Gutsche K, Randi E, Blank V, Fink D, Wenger R, Leo C, et al. Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-?B in inflammatory breast cancer cells. Free Radic Biol Med. 2016;101:129-142 pubmed publisher
Sun S, Elwood J, Greene W. Both amino- and carboxyl-terminal sequences within I kappa B alpha regulate its inducible degradation. Mol Cell Biol. 1996;16:1058-65 pubmed
product information
Catalog Number :
21985
Product Name :
pCMV4-3 HA/IkB-alpha
article :
doi
id2818
pubmed_id8622650
bacterial resistance :
Ampicillin
cloning :
backbonepCMV4-3HA
backbone_mutation
backbone_originAndersson,S. et al, J. Biol. Chem. 264 (14), 8222-8229 (1989)
backbone_size4874
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
growth notes :
Parental vector = pCMV4 3xHA; 3xHA inserted into MluI/HindIII of pCMV4.
origin :
37
pi :
alt_names
IkB-alpha
NFKBI
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5HindIII
promoter
sequencing_primer_3
sequencing_primer_5CMV-F
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesEDAID2, IKBA, MAD-3, NFKBI
geneNFKBIA
id4792
genbank_ids
mutation
nameI-kappa B alpha
shRNA_sequence
size1000
species
9606
Homo sapiens
tags
locationN terminal on backbone
tag3x HA
resistance markers :
176
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA