This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
T7-RelA
catalog :
21984
citations: 8
Reference
Yang J, Liu W, You J. Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential. PLoS Pathog. 2023;19:e1011598 pubmed publisher
Perez Santamarina E, Garcia Ruiz P, Martinez Rubio D, Ezquerra M, Pla Navarro I, Puente J, et al. Regulatory rare variants of the dopaminergic gene ANKK1 as potential risk factors for Parkinson's disease. Sci Rep. 2021;11:9879 pubmed publisher
Zhou X, Yu J, Cheng X, Zhao B, Manyam G, Zhang L, et al. The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming. Nat Immunol. 2019;20:879-889 pubmed publisher
Field J, Martens M, Mughal W, Hai Y, Chapman D, Hatch G, et al. Misoprostol regulates Bnip3 repression and alternative splicing to control cellular calcium homeostasis during hypoxic stress. Cell Death Discov. 2018;4:37 pubmed publisher
Prakoura N, Kavvadas P, Kormann R, Dussaule J, Chadjichristos C, Chatziantoniou C. NFκB-Induced Periostin Activates Integrin-β3 Signaling to Promote Renal Injury in GN. J Am Soc Nephrol. 2017;28:1475-1490 pubmed publisher
Kwon H, Choi G, Ryu S, Kwon S, Kim S, Booth C, et al. Stepwise phosphorylation of p65 promotes NF-?B activation and NK cell responses during target cell recognition. Nat Commun. 2016;7:11686 pubmed publisher
Yen H, Ooka T, Iguchi A, Hayashi T, Sugimoto N, Tobe T. NleC, a type III secretion protease, compromises NF-?B activation by targeting p65/RelA. PLoS Pathog. 2010;6:e1001231 pubmed publisher
Chen Lf -, Fischle W, Verdin E, Greene W. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science. 2001;293:1653-7 pubmed
product information
Catalog Number :
21984
Product Name :
T7-RelA
article :
doi10.1126/science.1062374
id2817
pubmed_id11533489
bacterial resistance :
Ampicillin
cloning :
backbonepEv3s
backbone_mutation
backbone_originMatthias P et al. Nucleic Acids Research (1989). 17(15): 6418
backbone_size5120
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
RelA
cloning
clone_methodRestriction Enzyme
cloning_site_3XbaI
cloning_site_5BamHI
promoter
sequencing_primer_3CTer primer: 5'-CCCTGAAAACTTTGCCCCCTCC-3'
sequencing_primer_5NTer primer 5'-GGGGGATCTTGGTGGCGTG-3'
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesAIF3BL3, CMCU, NFKB3, p65
geneRELA
id5970
genbank_ids
mutation For more details for this expression construct, as well as associated mutants, please contact: Dr. Lin-Feng Chen (lfchen@life.illinois.edu)
nameNFkB p65 subunit
shRNA_sequence
size1600
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagT7 gp10
resistance markers :
176
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA