This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
EGFP-hAgo2
catalog :
21981
citations: 12
Reference
Liu H, Li H, Jiang Z, Jin S, Song R, Yang Y, et al. A local translation program regulates centriole amplification in the airway epithelium. Sci Rep. 2023;13:7090 pubmed publisher
W xf6 rle E, Newman A, D Silva J, Burgio G, Grohmann D. Allosteric activation of CRISPR-Cas12a requires the concerted movement of the bridge helix and helix 1 of the RuvC II domain. Nucleic Acids Res. 2022;50:10153-10168 pubmed publisher
Willkomm S, Jakob L, Kramm K, Graus V, Neumeier J, Meister G, et al. Single-molecule FRET uncovers hidden conformations and dynamics of human Argonaute 2. Nat Commun. 2022;13:3825 pubmed publisher
Cialek C, Galindo G, Morisaki T, Zhao N, Montgomery T, Stasevich T. Imaging translational control by Argonaute with single-molecule resolution in live cells. Nat Commun. 2022;13:3345 pubmed publisher
Qifti A, Balaji S, Scarlata S. Deformation of caveolae impacts global transcription and translation processes through relocalization of cavin-1. J Biol Chem. 2022;298:102005 pubmed publisher
Pantazopoulou V, Delis A, Georgiou S, Pagakis S, Filippa V, Dragona E, et al. AGO2 localizes to cytokinetic protrusions in a p38-dependent manner and is needed for accurate cell division. Commun Biol. 2021;4:726 pubmed publisher
Wörle E, Jakob L, Schmidbauer A, Zinner G, Grohmann D. Decoupling the bridge helix of Cas12a results in a reduced trimming activity, increased mismatch sensitivity and impaired conformational transitions. Nucleic Acids Res. 2021;49:5278-5293 pubmed publisher
Lessel D, Zeitler D, Reijnders M, Kazantsev A, Hassani Nia F, Bartholomäus A, et al. Germline AGO2 mutations impair RNA interference and human neurological development. Nat Commun. 2020;11:5797 pubmed publisher
Hennessy E, van Solingen C, Scacalossi K, Ouimet M, Afonso M, Prins J, et al. The long noncoding RNA CHROME regulates cholesterol homeostasis in primate. Nat Metab. 2019;1:98-110 pubmed publisher
Golden R, Chen B, Li T, Braun J, Manjunath H, Chen X, et al. An Argonaute phosphorylation cycle promotes microRNA-mediated silencing. Nature. 2017;542:197-202 pubmed publisher
Miyazaki Y, Du X, Muramatsu S, Gomez C. An miRNA-mediated therapy for SCA6 blocks IRES-driven translation of the CACNA1A second cistron. Sci Transl Med. 2016;8:347ra94 pubmed publisher
Leung A, Calabrese J, Sharp P. Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A. 2006;103:18125-30 pubmed
product information
Catalog Number :
21981
Product Name :
EGFP-hAgo2
article :
doi10.1073/pnas.0608845103
id2815
pubmed_id17116888
bacterial resistance :
Kanamycin
cloning :
backboneEGFP-C1
backbone_mutation
backbone_originClontech
backbone_size4700
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
origin :
37
pi :
alt_names
eiF2C2, Ago2
cloning
clone_methodRestriction Enzyme
cloning_site_3BamHI
cloning_site_5EcoRI
promoter
sequencing_primer_3
sequencing_primer_5n/a
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesCASC7, EIF2C2, LESKRES, LINC00980, PPD, Q10
geneAGO2
id27161
genbank_ids
mutation
nameArgonaute 2
shRNA_sequence
size2580
species
9606
Homo sapiens
tags
resistance markers :
461
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA