This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Addgene
product type :
cDNA
product name :
pIS1 DICER1 long UTR
catalog :
21649
citations: 4
Reference
Gao J, Shi H, Juhlin C, Larsson C, Lui W. Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70. iScience. 2021;24:103264 pubmed publisher
Powers J, Tsanov K, Pearson D, Roels F, Spina C, EBRIGHT R, et al. Multiple mechanisms disrupt the let-7 microRNA family in neuroblastoma. Nature. 2016;535:246-51 pubmed publisher
Feinberg Gorenshtein G, Guedj A, Shichrur K, Jeison M, Luria D, Kodman Y, et al. MiR-192 directly binds and regulates Dicer1 expression in neuroblastoma. PLoS ONE. 2013;8:e78713 pubmed publisher
Mayr C, Bartel D. Widespread shortening of 3'UTRs by alternative cleavage and polyadenylation activates oncogenes in cancer cells. Cell. 2009;138:673-84 pubmed publisher
product information
Catalog Number :
21649
Product Name :
pIS1 DICER1 long UTR
article :
doi10.1016/j.cell.2009.06.016
id2868
pubmed_id19703394
bacterial resistance :
Ampicillin
cloning :
backbonepIS1
backbone_mutation
backbone_originAvailable from Addgene (#12179)
backbone_size4085
promoter
sequencing_primer_3
sequencing_primer_5
vector_types
Mammalian Expression
Luciferase
growth notes :
Long means that all functional alternative polyadenylation signals have been deleted.
origin :
37
pi :
alt_names
CM9
Dicer1
cloning
clone_methodRestriction Enzyme
cloning_site_3Not I
cloning_site_5Xba I
promoter
sequencing_primer_3EBV Reverse
sequencing_primer_5T7
site_3_destroyed
site_5_destroyed
entrez_gene
aliasesDCR1, Dicer, Dicer1e, GLOW, HERNA, K12H4.8-LIKE, MNG1, RMSE2, aviD
geneDICER1
id23405
genbank_ids
mutation
nameDicer 1 long UTR
shRNA_sequence
size4200
species
9606
Homo sapiens
tags
locationN terminal on backbone
tagLuciferase
resistance markers :
21
tags :
High Copy
company information
Addgene
490 Arsenal Way, Suite 100
Watertown, MA 02472
info@addgene.org
https://www.addgene.org
617.225.9000
headquarters: USA